Transplant Surgery Scientist Training Program

描述（由申请人提供）：移植有望扭转成千上万患有终末期器官疾病和代谢性疾病的美国人的临床病程。西北大学的移植项目在临床移植和移植相关研究方面处于全国领先地位。近年来，从事移植相关研究的移植外科医生和内科医生的数量有所减少。对从事科研工作缺乏热情的原因包括：1)科研培训经费支持不足；2)临床专科和专科培训与科研培训冲突；3)严格的研究方法教学不足；4)项目主管缺乏问责制，无法确保致力于临床研究事业的受训者在研究培训期间参与能够增强其竞争力的活动，从而在成为教员后获得独立资助。这项培训补助金的具体目标是：1)为受训人员提供津贴支助；2)与精通移植的学术临床医生合作，提供初级、中级和高级研究人员的指导；3)保护受训者不受竞争时间的临床活动的影响；4)维持能够扩大种族多样性和候选人质量的行政结构；5)提供跨领域的培训机会

DESCRIPTION (provided by applicant): Transplantation holds the promise of reversing the clinical course of thousands of Americans afflicted with end- stage organ disease, as well as metabolic diseases. Northwestern University's transplant program is a national leader in both clinical transplantation and transplantation-related research. The number of transplant surgeons and physicians engaged in transplantation-related research had decreased in recent years. Reasons given for the lack of enthusiasm in pursuing a research-related career include 1) insufficient financial support for research training, 2) conflict between clinical specialty and su-specialty training and research training, 3) inadequate teaching of rigorous research methodology, and 4) the lack of accountability on the part of program directors to ensure that trainees committed to careers in clinical investigation are engaged in activities during their research training that enhance their competitiveness to obtain independent funding when they become faculty members. The specific objectives of this training grant are to 1) provide stipend support for trainees; 2) provide mentorship by junior, mid-level, and senior investigators in collaboration with academic clinicians well versed in transplantation; 3) protect trainees from clinical activities that compete for their time; 4) sustain an administrative structure that expand the ethnic diversity and quality of the candidate pool; 5) provide training opportunities that span the spectrum from both basic/translational science to clinical/outcomes research at their intersection with clinical transplantation; and 6) continue an ongoing evaluation process for determining whether or not the program is meeting its goals and objectives. Trainees will be exposed to a rigorous base of classroom study in the disciplines necessary for successfully conducting transplant-related research, while being exposed to various other aspects of transplant surgery. There are two different tracks trainees can select from: NUTORC (the Northwestern University Transplant Outcomes Research Collaborative) and NUCTRIBE (the Northwestern University Collaborative for Transplant Research in Immunobiology and Biomedical Engineering). Both provide intensive, rigorous training by multidisciplinary senior, mid-level, and junior mentors, as well as classroom education. NUTORC trainees may choose between an MS in Health Services and Outcomes Research, an MS in Clinical Investigation, an MS in Epidemiology and Biostatistics or an MS in Healthcare Quality and Patient Safety. NUCTRIBE trainees may select coursework from many disciplines related to their research, chosen after consultation and approval by their mentors and the Executive Committee. Both tracks are required to take coursework in the responsible conduct of research. Both tracks uniquely prepare trainees to perform innovative, state-of-the-art research in transplant-related fields.