Cancer Center Support Grant

描述(由申请人提供)：加州大学洛杉矶分校琼森综合癌症中心(JCCC)是一个由NCI设计的矩阵中心，在实验室、临床和人口科学领域进行广泛的跨学科研究，整合了227名成员的活动。它的目标是：(1)转化基础研究，以降低癌症的发病率、发病率和死亡率，并改进预防、检测、诊断和治疗；(2)作为社区资源，为非专业人员和卫生保健专业人员赞助和开展信息活动，并实施将社区与JCCC的研究和服务联系起来的外联计划；(3)通过促进多学科诊断、治疗、生存和预防服务，提供最高质量的临床护理。在过去的资助周期中，参加临床试验的患者中有45%参加了机构研究。JCCC的总资金基数为1.89亿美元，其中NCI资金为4,070万美元。此外，在本报告所述期间的3 744份出版物中，32%是在影响较大的期刊上发表的，40%是方案间出版物，25%是方案内出版物。以下11个项目和9个共享资源需要继续支持。

DESCRIPTION (provided by applicant): The University of California Los Angeles Jonsson Comprehensive Cancer Center (JCCC) is an NCI-designed matrix center conducting a wide range of inter-disciplinary research in the areas of laboratory, clinical and population sciences integrating the activities of 227 members. Its goals are to: (1) translate basic research to reduce cancer incidence, morbidity and mortality, and to improve prevention, detection, diagnosis and treatment; (2) serve as a community resource to sponsor and conduct informational activities for lay people and health care professionals and to implement outreach programs linking the communities to the research and services of JCCC; (3) provide the highest quality of clinical care by promoting multidisciplinary diagnostic, treatment, survivorship and prevention services. Over the past funding cycle 45% of patients enrolled in clinical trials were enrolled in Institutional studies. The total funding base for the JCCC is $189 million with $40.7 million in NCI funding. In addition, of 3,744 total publications in the reporting period 32% were published in high-impact journals, 40% were interprogrammatic and 25% were intraprogrammatic. Continuing support is requested for the following 11 Programs and 9 Shared Resources.