Core A: Administrative p386-402

拟议的TCORS的首要主题是开发改进的模型， 产品监管战略，整合1）烟草使用对健康成本的经济影响，2）风险 感知、感知的可接受性、消费者对亲烟草营销和反烟草营销的反应 烟草使用的信息和其他社会决定因素，以及3）烟草使用导致的风险迅速变化 和二手烟暴露，表现为心血管和肺功能障碍。的 行政核心将是中央组织单位，负责监督TCORS的所有方面， 包括五个完整的科学研究项目，两个初步发展项目，两个核心， 研究培训和教育部分，以及未来发展的征集和选择 项目这一领导和监督组织的基础设施是通过以下资源建立的： 加州大学旧金山分校烟草控制研究与教育中心（CTCRE），一个跨部门的学术机构， UCSF于2001年创建的一个单位，作为广泛的研究，教育和公众的焦点 与烟草控制的各个方面有关的服务活动。Stanton Glantz博士， 拟议的TCORS是CTCRE的创始主任，Pamela Ling博士是联合调查员， 拟议的TCORS执行委员会成员是CTCRE副主任和 CTCRE博士后培训计划。Neal Benowitz博士，也是联合调查员和 执行委员会，通过其博士后培训积极参与CTCRE的悠久历史 计划，并作为主要研究员的中心赠款二手烟涉及CTCRE教师。 CTCRE坚定地致力于研究，培训和公众参与，并提供强大的 平台，以支持拟议的TCORS。 行政核心的目标将通过实现四个具体目标来实现：1）提供 对TCORS进行强有力的科学领导; 2）对所有TCORS进行财政监督和管理 活动; 3）为TCORS提供行政支持;以及4）为培训提供行政支持 活动和发展项目的选择。

The overarching theme of the proposed TCORS is the development of improved models to inform tobacco product regulatory strategies that integrate 1) economic impacts of tobacco use on health costs, 2) risk perceptions, perceived acceptability, consumer responses to pro-tobacco marketing and anti-tobacco messages and other social determinants of tobacco use, and 3) rapid changes in risk due to tobacco use arid secondhand smoke exposure as manifest in cardiovascular and pulmonary dysfunction. The Administrative Core will be the central organizational unit that will oversee all aspects of the TCORS, including the five full scientific Research Projects, two initial Developmental Projects, two Cores, the Research Training and Education Component, and the solicitation and selection of future Developmental Projects. The infrastructure for this organization of leadership and oversight exists through the resources of the UCSF Center for Tobacco Control Research and Education (CTCRE), an interdepartmental academic unit that UCSF created in 2001 to serve as a focal point for a broad range of research, education, and public service activities related to all aspects of tobacco control. Dr. Stanton Glantz, the Principal Investigator for the proposed TCORS, is the founding Director of the CTCRE, and Dr. Pamela Ling, a Co-lnvestigator and Executive Committee member for the proposed TCORS, is Associate Director of the CTCRE and Director of the CTCRE Postdoctoral Training Program. Dr. Neal Benowitz, also a Co-lnvestigator and member of the Executive Committee, has a long history of active participation in CTCRE through its Postdoctoral Training Program and as Principal Investigator for a center grant on secondhand smoke involving CTCRE faculty. The CTCRE is strongly committed to research, training, and public engagement and provides a strong platform to support the proposed TCORS. The goals of the Administrative Core will be accomplished by carrying out four specific aims: 1) provide strong scientific leadership for the TCORS; 2) provide fiscal oversight and management of all TCORS activities; 3) provide administrative support for the TCORS; and 4) provide administrative support for training activities and the selection of Developmental Projects.