Imroving transplantation outcomes

对于大多数患者来说，将捐赠者的健康干细胞移植到患有血癌的接受者体内(干细胞移植)是最有效的治疗方法。不幸的是，这一过程导致了不受欢迎的、往往是致命的副作用，包括感染，这是一种称为移植物抗宿主病的排斥过程，在一些患者中，白血病仍然会复发。这项研究将改进新的治疗方法，重点是克服这些限制和改善移植结果

The transplantation of healthy stem cells from a donor into a recipient with blood cancer (stem cell transplantation) is the most effective curative therapy for the majority of patients. Unfortunately this process results in unwanted, often fatal, side effects including infection, a rejection process known as graft-versus-host disease and in some patients, the leukaemia still recurs. This research will refine new treatments focused on overcoming these limitations and improving transplant outcome