Center for AIDS Research

描述(由申请人提供)：纽约大学医学中心的艾滋病研究中心由70名临床和基础科学研究人员组成，他们在曼哈顿下城的三个相邻机构和河对岸的纽瓦克的一个机构进行研究。这些科学家隶属于纽约大学医学院，尽管他们的实验室和研究诊所位于曼哈顿退伍军人医院、贝尔维尤医院、纽约公共卫生研究所以及包括Tisch医院和Skirball研究所在内的医学院大楼。自1980年发现第一名患者以来，纽约大学的研究人员为我们理解这种疾病的病毒学、免疫学、流行病学以及感染和肿瘤并发症做出了许多重要贡献。纽约大学的临床医生正在照顾超过4,000名HIV感染者，我们的临床研究努力吸引了来自整个大都市地区数千名HIV+受试者的更多患者。这项研究目前得到了超过2500万美元的艾滋病相关资金的支持，其中包括来自美国国立卫生研究院的每年超过1500万美元的资金。CFAR支持这一富有成效的研究计划，并通过四个共享的核心设施和发展基金来提高其效率，以支持年轻的研究人员和新的研究机会。CFAR还将具有相似兴趣的研究人员聚集到几个研究项目中，以促进创新和合作。 核心A：行政核心(瓦伦丁，F) 描述(由申请人提供)：行政股(核心)为CFAR提供全面的领导和行政管理。行政部门由弗雷德·瓦伦丁医学博士领导，并得到两位副主任丹·利特曼医学博士和威廉·博尔科斯基临床研究博士的支持。行政当局的责任分为两类：1)在扩大与艾滋病毒有关的合作和翻译研究方面提供积极主动的领导；2)确保中心的多种要素作为一个中心一起运作，确保整体大于其各部分的总和。高级领导层确立了该中心的目标，并通过该中心的方案和核心结构，为艾滋病毒研究的互动、发展和支持创造了最佳环境。主任还与管理人员Andrea Barrett女士和Irini Albanti女士合作，确保中心主要行政职能的顺利运作。这些包括：指导CFAR业务的政策；预算管理；内部和外部通信系统；CFAR活动的规划和评价；协助调查人员以及与发展办公室合作为CFAR筹集资金。行政核心的职能主要是提供维持CFAR活动所需的行政支助系统和管理工具。该核心负责促进和跟踪其成员的科学生产力和进步。核心还组织和扩大我们的外联和国际科学和教育活动。

DESCRIPTION (provided by applicant): The Center for AIDS Research at NYU Medical Center comprises seventy clinical and basic science investigators performing research in three contiguous institutions in lower Manhattan and one across the river in Newark. These scientists are affiliated with the NYU School of medicine, although their laboratories and research clinics are located at the Manhattan VA Hospital, Bellevue Hospital, the New York Public Health Research Institute, as well as the School of Medicine buildings, including Tisch Hospital and Skirball Institute. Many important contributions to our understanding of the virology, immunology, epidemiology, and the infections and neoplastic complications of this disease have been made by NYU investigators since they identified their first patient in 1980. NYU clinicians are caring for over 4,000 HIV-infected individuals, and our clinical research efforts attract additional patients from the several thousands of HIV + subjects throughout the metropolitan region. This research is currently supported by over $25 M in AIDS-related funding, which includes over $15 M in yearly funding from the NIH. The CFAR supports this productive program of research and increases its efficiency by four shared core facilities, and developmental funds to support young investigators and new research opportunities. The CFAR also brings together investigators with similar interests into several research programs to facilitate innovation and collaboration. CORE A: Administrative Core (Valentine, F) DESCRIPTION (provided by applicant): The Administration Unit (Core) provides overall leadership and administrative management to the CFAR. The Administration is directed by Fred Valentine, M.D., with the support of two Associate Directors, Dan Littman, M.D., Ph.D. for Basic Science and William Borkowsky, M.D., for Clinical Research. The responsibilities of the Administration fall into two categories: 1) Providing proactive leadership in expanding HIV-related collaborative and translational research, 2) Ensuring that the multiple elements of the Center function together as a Center, that the whole is in fact greater than the sum of its parts. The senior leadership establishes the goals of the Center and, through the Center's programmatic and core structure, creates the optimal environment for interaction, growth and support of HIV research. The Director also works with the Administrators, Ms. Andrea Barrett and Irini Albanti, to ensure the smooth operation of the Center's chief administrative functions. These include: policies to guide the CFAR operations; budgetary stewardship; internal and external communication systems; planning and evaluation of CFAR activities, helping investigators and working with the development office on fund raising for CFAR. The Administrative Core functions primarily to provide the administrative support systems and management tools needed to maintain the CFAR's activities. This Core is responsible for fostering and tracking the scientific productivity and progress of its members. The Core also organizes and expands our outreach and international scientific and educational activities.