UNC Center for AIDS Research

北卡罗来纳大学CFAR是由三个相辅相成的机构组成的联盟：北卡罗来纳大学教堂山分校、国际家庭健康组织(FHI)和三角研究所(RTI)。在过去的七年里，我们的CFAR不断发展，以满足我们成员的不同需求，并在机构内发挥领导作用。在这次续签申请中，我们建议继续使用以前的七个核心，并增加两个新的核心：免疫学核心和国际核心。随着续签的成功，我们将大大增加机构支持，包括新的指定、毗连的空间和分配新的教员职位。此外，我们将利用CFAR资金创建一个资源池，可用于促进进一步雇用艾滋病毒/艾滋病研究人员。我们的CFAR在制定实时识别急性艾滋病毒感染的战略方面发挥了核心作用，我们现在与北卡罗来纳州合作，识别这些人并将他们纳入研究方案。在CFAR的支持和领导下，我们已经将 新的治疗策略，以改变这些人的疾病进程，我们将在这些领域进行临床试验。我们的气候变化框架对国际范围内的艾滋病毒/艾滋病研究有很大的承诺，新的国际核心将允许对这一努力提供更有效的支持。我们CFAR的成员成功地将艾滋病毒候选疫苗带入人体试验，我们新的免疫学核心代表了 努力为其他正在进行的疫苗和临床免疫学研究提供更广泛的支持。我们坚定地致力于支持翻译研究，我们的三个核心保持了CLIA的批准，同时与临床核心密切合作。最后，我们通过将北卡罗来纳州历史上少数族裔大学的艾滋病毒/艾滋病研究人员作为潜在的发展奖获得者，将我们的发展核心的使用扩展到包括外展和指导。这是我们的第二次更新，我们的CFAR在一个协调良好的领导层下运作，积极促进和支持专注于一些关键研究领域的跨学科研究。CFAR的支持对于维持这一努力至关重要，该努力旨在最大限度地发挥CFAR成员的潜力。

The UNC CFAR is a consortium of three complementary institutions: UNC Chapel Hill, Family Health International (FHI), and Research Triangle Institute (RTI). Over the last seven years our CFAR has grown to serve the diverse needs of our membership and to provide leadership within the institutions. In this renewal application we propose to continue with our previous seven cores and to add two new cores: an Immunology Core and an International Core. With a successful renewal we will greatly increase the institutional support, including new designated, contiguous space and the allocation of new faculty slots. In addition, we will use CFAR funding to create a pool of resources that can be leveraged to promote further hiring of HIV/AIDS researchers. Our CFAR has played a central role in the development of a strategy to identify acute HIV infections in real time, and we now partner with the State of North Carolina to identify such people and enroll them into research protocols. With CFAR support and leadership we have conceptualized new therapeutic strategies to alter the course of the disease in these people, and we will pursue clinical trials in these areas. Our CFAR has a substantial commitment to HIV/AIDS research in the international setting and the new International Core will allow more effective support for that effort. Members of our CFAR have successfully brought an HIV vaccine candidate to human trials, and our new Immunology Core represents an effort to bring broader support to other ongoing vaccine and clinical immunology studies. We have a strong commitment to supporting translational research, with three of our cores maintaining CLIA approval while working closely with the Clinical Core. Finally, we have extended the use of our Developmental Core to include outreach and mentoring by including HIV/AIDS researchers at historically minority universities across North Carolina as potential Developmental Awardees. With this, our second renewal, our CFAR is functioning with a well coordinated leadership that is actively promoting and supporting interdisciplinary research focused on a number of critical research areas. CFAR support is essential to maintain this effort signed to maximize the potential of the CFAR membership.