From Adolescence to Adulthood: Persons with and without Diabetes

描述（由申请人提供）：本申请是对有和没有糖尿病的青年进行的纵向研究的第二次竞争性延续。在2002年，我们招募了132名患有糖尿病的儿童和131名没有糖尿病的儿童，他们在六年级，七年级或八年级，平均年龄为12岁。该研究的重点是预测两组青少年成功过渡的心理社会因素，以及预测糖尿病青年与糖尿病有关的困难。在2007年，我们收到了5年的竞争延续，以检查从高中到成年初显的开始过渡。在这项研究（正在进行中）中，我们正在研究高中高年级和1、2年后的青年。在拟议的应用程序中，我们专注于成年初显期（EA）在那些有和没有糖尿病。我们提出了一个三波纵向研究这些EA跨越22-24岁。22至24岁是检查健康行为和心理健康的关键。对于那些糖尿病患者来说，这些年是从儿科医疗保健系统转移到成人医疗保健系统的关键。平均患糖尿病15年，我们也可以观察并预测糖尿病相关并发症的发生。我们有四个主要目标：（1）确定糖尿病患者和非糖尿病患者在社会心理功能、健康行为以及与教育、就业、人际关系和财务相关的成年期结果方面是否存在差异;（2）在糖尿病患者中，捕捉从儿科医疗保健系统转移到成人医疗保健系统的情况，检查所做的医疗保健选择，并评估这些选择对糖尿病健康的影响;（3）在糖尿病患者中，检查糖尿病相关并发症的早期指标，并将并发症发生率与可比队列进行比较（根据糖尿病的年龄和病程）来自糖尿病并发症流行病学试验;及（4）利用“风险与抵抗力架构”预测糖尿病及非糖尿病的EA的心理、行为及身体健康。我们将连续三年每年访问一次EAs，让他们通过笔记本电脑完成心理社会调查，以获得糖尿病和健康参与者的一系列一般健康指标（例如，BMI），并获得糖尿病相关并发症的详细评估（例如，神经病、肾病）由受过训练的护士（仅1年和3年）给药。这项研究的结果将用于识别有精神和身体健康困难风险的EA。

DESCRIPTION (provided by applicant): This application is for a second competing continuation of a longitudinal study of youth with and without diabetes. In 2002, we enrolled 132 children with diabetes and 131 children without diabetes who were in the 6th, 7th, or 8th grade and on average 12 years old into a longitudinal study. The focus of that study was on the psychosocial factors that predicted a successful transition through adolescence for both groups and that predicted diabetes-related difficulties for youth with diabetes. In 2007, we received a 5-year competing continuation to examine the transition out of high school into the onset of emerging adulthood. In that study (in progress), we are examining youth in their senior year of high school and 1 and 2 years later. In the proposed application, we focus on the stage of emerging adulthood (EA) in those with and without diabetes. We propose a three-wave longitudinal study of these EAs spanning the ages of 22-24. The ages 22 through 24 are critical for the examination of health behaviors and psychological well-being. For those with diabetes, these years are critical in terms of the transfer out of the pediatric health care system into the adult health care system. Having had diabetes for an average of 15 years, we also may observe and be able to predict the onset of diabetes-related complications. We have four primary aims: (1) To determine if there are differences between persons with and without diabetes in psychosocial functioning, health behaviors, and emerging adulthood outcomes related to education, employment, relationships, and finances; (2) Among those with diabetes, to capture the transfer out of the pediatric health care system into the adult health care system, to examine health care choices made, and to evaluate the implications of these choices for diabetes health; (3) Among those with diabetes, to examine early indicators of diabetes-related complications and compare the rate of complications to a comparable cohort (in terms of age and length of diabetes) from the Epidemiology of Diabetes Complications Trial; and (4) To utilize a "Risk and Resistance Framework" to predict psychological, behavioral, and physical health among EAs with and without diabetes. We will visit EAs once a year for three consecutive years to have them complete a psychosocial survey via a laptop computer, to obtain a series of general health measures for both diabetes and healthy participants (e.g., BMI), and to obtain a detailed assessment of diabetes-related complications (e.g., neuropathy, nephropathy) administered by a trained nurse (only years 1 and 3). The results of this study will be used to identify EAs at risk for mental and physical health difficulties.