Advancing Competitive Biomedical Research in Puerto Rico

 描述（由申请人提供）：波多黎各IDEA生物医学研究卓越网络（PR-INBRE）的更新申请将通过作为开展多学科研究的平台，加强波多黎各生物医学研究能力的原始目标。这一目标将得到四个专题重点领域的支持：神经科学，分子医学，药物开发，环境和行为研究;在上一个资助期间开发的生物信息学基础设施的支持。新的领导机构，波多黎各医学科学校园大学（UPR-MSC）是一个完整的学术健康中心和一个主要的西班牙裔服务机构。UPR-MSC将加强牵头机构和合作机构之间的合作，提高其生物医学相关研究的能力，并为11所小学本科院校（PUI），3所医学院，1所专业学校和2所研究密集型机构的17名成员PR-INBRE网络提供科学领导和后勤支持。PR-INBRE预计将使89,712名攻读博士学位的全日制学生受益，医学博士，医学硕士，和B. S。STEM、医学和生物医学学科的学位。PR-INBRE的行政，生物信息学，仪器和教育核心将为教师，博士后研究员，本科生，医学生和研究生实施创新的研究培训和职业发展活动。这些活动将由发展研究项目计划赞助，该计划支持为年轻研究人员提供各种资助和指导。此外，还将支持学生的研究指导和工资支持，INBRE机构的访问演讲者计划，技术培训研讨会，专业课程和旅行奖励。1.加强PR-INBRE网络牵头机构和伙伴机构的生物医学专门知识和研究基础设施。2-促进研究教师，博士后研究员，研究生和本科生的研究代表性不足的群体的发展。3-提高生物医学劳动力的科学和技术能力。改进对研究项目调查人员的监督，更加重视研究导师的有效性，加强外部和内部评估，跟踪每项计划活动的成果，将是该计划的一个标志。通过与区域INBRE和COBRE计划的合作，我们将利用我们的研究资源和科学专业知识，丰富研究和培训机会的数量和质量。一个统一的行政结构，加上对INBRE目标的强有力的机构承诺，将创造一个有利的环境，提高网络中研究的生产力和质量，并导致招聘和留住有才华的研究人员。我们希望维持一个充满活力的生物医学培训管道，有助于生物医学劳动力的多样性，并最终通过研究影响人类健康。

 DESCRIPTION (provided by applicant): This renewal application of the Puerto Rico IDeA Networks of Biomedical Research Excellence (PR-INBRE) will reinforce the original goal to strengthen the biomedical research capacity in Puerto Rico by serving as a platform for conducting multidisciplinary research. This objective will be augmented by the support of four thematic focus areas: Neuroscience, Molecular Medicine, Drug Development, Environmental and Behavioral Research; buttressed by the Bioinformatics infrastructure developed during the previous funding period. The new lead institution, the University of Puerto Rico Medical Sciences Campus (UPR-MSC) is a complete academic health center and a predominantly Hispanic-serving institution. The UPR-MSC will strengthen collaborations between lead and partner institutions, enhance their capacity for biomedically relevant research, and provide scientific leadership and logistical support for a 17-member PR-INBRE network of 11 Primarily Undergraduate Institutions (PUIs), 3 Medical Schools, 1 Professional School, and 2 Research-intensive institutions. The PR-INBRE is expected to benefit the ~89,712 full time students pursuing Ph.D., M.D., M.S., and B.S. degrees in STEM, Medicine, and Biomedical disciplines. Administrative, Bioinformatics, Instrumentation, and Education Cores of the PR-INBRE will implement innovative research training and career development activities for faculty, postdoctoral Fellows, undergraduate, medical, and graduate students. These activities will be sponsored by a Developmental Research Project Program supporting a variety of funding and mentoring initiatives for young investigators. Also supported will be research mentoring and salary support for students, a Visiting Speaker Program for INBRE institutions, Technical Training Workshops, Specialized Courses, and Travel Awards. The Specific aims of PR-INBRE are: 1-Strengthen the PR-INBRE network lead and partner institutions' biomedical expertise and research infrastructure. 2- Contribute to the development of research faculty, postdoctoral Fellows, graduate and undergraduate students of underrepresented groups in research. 3- Enhance the science and technology competency of the biomedical workforce. Improved oversight of research project investigators and greater emphasis on effectiveness of Research Mentors coupled with intensification of external and internal evaluation and tracking of outcomes for every program activity will be a hallmark of this program. Through collaborations with regional INBRE and COBRE programs, we will leverage our research resources and scientific expertise, and enrich the number and quality of research and training opportunities. A unified administrative structure coupled with a strong institutional commitment to the INBRE goals will create a nurturing environment that will raise the productivity and quality of research in the network, and result in the recruitment and retention of talented researchers. We expect to sustain a vigorous biomedical training pipeline that contributes to diversity in the biomedical workforce, and ultimately impact human health through research.