Annual American Society for Rickettsiology (ASR) Workshop

描述(由申请人提供)：作为美国立克次体学会(ASR)成员的国际研究人员社区在从澳大利亚到津巴布韦的国家都有代表，当然，包括美国和欧洲。病媒传播的立克次体病原体的全球出现助长了这种广泛的地理代表性。ASR的年度会议甚至在出版之前就促进了发现和资源的科学交流。这就形成了一个相互交织的合作成员结构，这非常有利于该领域本身的进步，并促进了年轻研究人员与知名科学家之间的联系。在每次会议上，组织者都会赞助每个参加实验室的初级成员(主要是学生、博士后研究人员和助理教授)，特别是为了加强新信息的流动，并鼓励年轻的立克病专家留在该领域。在去年会议结束时，组织者邀请所有与会者进行讨论，以确定被视为推动立克次体病理学进步的最优先研究领域。因此，我们建议在ASR年度会议的框架内组织一个为期一天半的研讨会，讨论“立克次体中基因表达的调控”这一中心主题。这将广泛地包括节肢动物媒介(Abdu Azad UMD，Kevin Macaluso LSU)和哺乳动物宿主(Jere McBride UTMB，Matt Welch UCB，Yasuko Rikihisa OSU)成功定植的分子决定因素，节肢动物(Joao Pedra UCR，Viveka Vadyvaloo WSU)和哺乳动物(Guy Palmer WSU，Nahed Ismail UPMC)的防御反应，以及病原体的基因操作，以确定协调这种相互作用的调控机制(Ulrike Munderloh UMN，Dan Rockey OR，Daniel Voth AR)。研讨会将包括主要演讲者的口头陈述，以及由初级教师、博士后科学家和提交摘要的学生中的每一位主要演讲者挑选的额外演讲者。在口头陈述之后将进行深入的讨论。口头陈述会议与中心主题内的海报会议相辅相成。来自任职人数不足的群体的成员将被积极招募为演讲者和海报主持人。主要演讲者将被要求将海报组织成大约五到六个人的小组，并将在海报演示者和参与会议的与会者中领导他们的讨论。在会议主席的帮助下，并与演讲者协作，将总结口头和海报发言的主要影响，包括讨论，并在会议结束后公布。

DESCRIPTION (provided by applicant): The international community of researchers who are members of the American Society for Rickettsiology (ASR) is represented in countries from Australia to Zimbabwe, including, of course, the USA and Europe. This wide geographic representation is fed by the global emergence of vector-borne rickettsial pathogens. The annual meetings of the ASR foster scientific exchange of discoveries and resources even before publication. This has resulted in an interwoven fabric of cooperating members that is highly conducive to the advancement of the field itself and facilitates connections between young investigators with established scientists. At every meeting, the organizers sponsor a junior member (primarily students, postdoctoral researchers and assistant professors) from each attending laboratory, specifically with the aim to strengthen the flow of new information, and to encourage young rickettsiologists to remain in the field. At the end of last year's meeting the organizers invited a discussion among all attendees to identify research areas viewed to be of highest priority for driving advances in rickettsiology. As a result, we propose to organize a 1 and 1/2-day workshop within the framework of the annual ASR meeting that addresses the central theme of "Regulation of Gene Expression in Rickettsiae." This will broadly include molecular determinants of successful colonization of the arthropod vector (Abdu Azad UMD, Kevin Macaluso LSU) and the mammalian host (Jere McBride UTMB, Matt Welch UCB, Yasuko Rikihisa OSU), defensive responses of arthropods (Joao Pedra UCR, Viveka Vadyvaloo WSU) and mammals (Guy Palmer WSU, Nahed Ismail UPMC), and genetic manipulation of pathogens to identify the regulatory mechanisms that coordinate this interplay (Ulrike Munderloh UMN, Dan Rockey OR, Daniel Voth AR). The workshop will comprise oral presentations by the key speakers, and additional speakers who will be selected by each key speaker from junior faculty, postdoctoral scientists and students who have submitted abstracts. An in-depth discussion session will follow oral presentations. Oral presentation sessions are complemented by poster sessions that fall within the central theme. Members from underrepresented groups will be actively recruited as speakers and poster presenters. Key speakers will be asked to organize posters into groups of about five - six each, and will lead their discussion among poster presenters and participating meeting attendees. With the help of session chairs, and in collaboration with presenters, the major impacts of oral and poster presentations will be summarized, including the discussions, and published following the meeting.