The UCLA South African Trauma Research Training Program

描述(由申请者提供)：加州大学洛杉矶分校/南非创伤培训研究(PHODISO)计划寻求额外五年的资金，为未来的调查人员做好准备，在南非高度的人际和社区暴力和故意伤害的背景下进行创伤暴露和伤害预防的研究。Phodiso计划是加州大学洛杉矶分校和南非研究联盟(SARC)之间的国际合作，该联盟包括人文科学研究理事会(HSRC)、西北大学(NWU)和开普敦大学(UCT)，基于NIH资助的三个项目：1)埃班项目，这是一项随机临床试验，测试对艾滋病毒血清不合的非裔美国夫妇进行的文化一致性干预(R01；2001-2011年)；2)南非妇女强奸的后果(Fulufhelo项目)，一项研究南非妇女强奸的短期和长期心理社会后遗症的研究(R03；2009-2012年)；3)艾滋病毒/艾滋病翻译培训方案(HATT)，面向对艾滋病毒/艾滋病、心理健康和药物滥用及相关的共病差异感兴趣的少数民族博士后学者和早期职业调查人员(R25；2009-2011年)。在生态和社会学习理论的指导下，Phodiso学者的研究重点将是将南非创伤暴露的负面健康和心理健康影响降至最低，特别是抑郁症和创伤后应激障碍(PTSD)。我们的多学科培训计划在过去五年中发展起来，建议扩大到对生物和遗传标记以及应激介质的调查和培训，从而成为更全面的生物行为创伤培训计划。在最初的供资期间，8名学者接受了培训，现在将组成技术咨询小组(TAG)。对于这次续签，加州大学洛杉矶分校和南加州大学的核心教师和TAG将在全国范围内进行申请程序，每年挑选一名早期职业研究候选人，获得为期两年的博士后奖学金。学者将接受研究指导，包括每年在加州大学洛杉矶分校进行的四分之一研究(即3个月)、一次遴选和规划会议以及一次短期创伤研讨会。学者们将在南非开展自己的研究项目，作为这一领域未来研究的基础，并与南盟主办大学和TAG导师密切合作。Phodiso创伤培训计划和学者的研究职业生涯将随着时间的推移进行跟踪。具体地说，将评估和记录培训计划的可持续性、与学术、私人和政府支持的机构的整合，以及学者建立和维持独立研究事业的能力。未来的目标将包括鼓励南非政府支持、支持和采用Phodiso计划，将其作为跨文化创伤研究培训的成功和可复制的模式。 公共卫生相关性：加州大学洛杉矶分校/南非创伤培训研究(PHODISO)计划寻求额外五年的资金，为未来的调查人员做好准备，以便在南非高水平的人际和社区暴力和故意伤害的背景下进行创伤和伤害暴露的研究。作为加州大学洛杉矶分校和包括人文科学研究理事会(HSRC)、西北大学(NWU)和开普敦大学(UCT)在内的南非研究联盟(SARC)之间的国际合作，Phodiso的公共卫生使命是：1)增加训练有素的南非创伤研究人员的数量；2)将研究成果转化为文化契合的创伤和伤害预防和治疗计划；3)促进社区能力建设和基础设施建设，使南非人民受益。

DESCRIPTION (provided by applicant): The UCLA/South African Trauma Training Research (Phodiso) Program seeks five additional years of funding to prepare future investigators to conduct research on trauma exposure and injury prevention in the context of South Africa's high levels of interpersonal and community violence and intentional injuries. The Phodiso Program is an international collaboration between UCLA and the South African Research Consortium (SARC), which includes the Human Sciences Research Council (HSRC), North-West University (NWU), and University of Cape Town (UCT) and is based on three NIH-funded projects: 1) The Eban Project, a randomized clinical trial testing a culturally congruent intervention for HIV serodiscordant African American couples (R01; 2001-2011); 2) The Aftermath of Rape Among South African Women (The Fulufhelo Project), a study examining the short and long-term psychosocial sequelae of rape among South African women (R03; 2009-2012); and 3) The HIV/AIDS Translational Training Program (HATT) for racial and ethnic minority postdoctoral Scholars and early career investigators interested in studying HIV/AIDS, mental health and substance abuse and associated co-morbid disparities (R25; 2009-2011). Guided by ecological and social learning theories, the focus of the Phodiso Scholar's research will be to minimize the negative health and mental health effects of trauma exposure, specifically depression and post-traumatic stress disorder (PTSD), in South Africa. Developed over the past five years, our multidisciplinary training program proposes to expand to investigate and train on biologic and genetic markers and mediators of stress and thus, to be a more comprehensive biobehavioral trauma training program. During the initial funding period, eight scholars were trained and will now compose the Technical Advisory Group (TAG). For this renewal, the UCLA and SARC core faculty and TAG will conduct a countrywide application process to select one early career research candidates per year for a two-year postdoctoral fellowship. Scholars will receive research mentorship including a quarter of study (i.e., a 3-month period) at UCLA, one selection and planning meeting and one short-term trauma workshop each year in South Africa. Scholars will conduct their own research projects in South Africa as a basis for future studies in this field, as well as work closely with their SARC host university and TAG mentors. The Phodiso Trauma Training program and the research careers of the scholars will be tracked over time. Specifically, the sustainability of the training program and integration into academic, private, and government-supported agencies and the Scholar's ability to establish and sustain independent research careers will be evaluated and documented. Future goals will include encouraging the South African government to support, endorse and adopt the Phodiso program as a successful and replicable model of cross-cultural trauma research training. PUBLIC HEALTH RELEVANCE: The UCLA/South African Trauma Training Research (Phodiso) Program seeks five additional years of funding to prepare future investigators to conduct research on trauma and injury exposure in the context of South Africa's high levels of interpersonal and community violence and intentional injuries. As an international collaboration between UCLA and the South African Research Consortium (SARC), which includes the Human Sciences Research Council (HSRC), North-West University (NWU), and University of Cape Town (UCT), Phodiso's public health mission is to: 1) Increase the number of well-trained South African trauma researchers; 2) Translate research findings to culturally congruent trauma and injury prevention and treatment programs and; 3) Facilitate building of community capacity and infrastructure that benefit the people of South Africa.