IBMS Sun Valley Workshop on Musculoskeletal Biology

本申请为2013年8月4日至7日在爱达荷州太阳谷举行的太阳谷骨骼生物学研讨会年度会议提供支持。研讨会有40年的传统，强调初级教师和学生的积极参与。研讨会促进了跨学科的交流，不同寻常的是，讨论的时间等于或超过了正式演讲的时间。研讨会的目标是：(1)致力于与骨和关节疾病的发病、预防和治疗相关的分子、组织和生物力学过程的多学科基础和临床合成；(2)发展基础和临床研究者之间的对话；(3)为初级教师和学生提供培训讲习班，帮助弥合学科之间的差距；(4)为学生培训提供论坛，并为初级研究人员提供在小组环境中与更资深的科学家交谈的机会。研讨会与国际骨与矿物协会（IBMS）之间的伙伴关系改善了市场营销，特别是在国际上，并通过IBMS BoneKEy广播电子邮件和IBMS网站上的链接提供了最大的知名度。今年，研讨会将讨论几个主题。一个与“影响骨骼的疾病过程”相关（糖尿病和骨骼；CKD-MBD：复杂系统生物学中的病理生理学和实验技术）。第二部分涉及“细胞群中的信号传导”（骨和软骨界面的细胞相互作用和信号传导；骨髓和造血干细胞生态位）。关于骨疲劳、应力性骨折和骨修复的会议跨越了这两个主题，讨论了应力性骨折修复中的骨细胞信号，并将其与非典型股骨骨折联系起来

DESCRIPTION (provided by applicant): Description This application requests support for the annual meeting of the Sun Valley Workshop on Skeletal Biology held in Sun Valley, Idaho, August 4-7, 2013. The Workshops have a 40 year tradition, and emphasize active participation of junior faculty and students. The Workshops promote interdisciplinary communication, and are unusual in that discussion time equals or exceeds time allotted for formal presentation. The goals of the Workshop are to (1) work toward a multidisciplinary basic and clinical synthesis of molecular, tissue and biomechanical processes related to the pathogenesis, prevention and treatment of bone and joint diseases; (2) develop a dialogue between basic and clinical investigators; (3) provide training workshops for junior faculty and students that help bridge the gaps between disciplines; (4) provide a forum for student training and the opportunity for junior investigators to talk with more senior scientists in a small group setting. A partnership between the Workshop and the International Bone and Mineral Society (IBMS) has improved marketing, especially internationally, and provides maximum visibility through IBMS BoneKEy broadcast emails and links on the IBMS website. This year, the Workshop will address a couple of themes. One is related to "Disease Processes that Affect Bone" (Diabetes and Bone; CKD-MBD: Pathophysiology and Experimental Techniques in a Complex Systems Biology). A second addresses the area of "Signaling Among Cell Populations" (Cell Interactions and Signaling at the Bone and Cartilage Interface; Bone Marrow and the Hematopoietic Stem Cell Niche). A session on Bone Fatigue, Stress Fractures and Bone Repair cuts across both themes by addressing osteocyte signaling in the repair of stress fractures, relating this to atypical femoral fractures. Many opportunities are provided for junior investigators to interact with more senior investigators. The Sunday evening session is set aside for a Plenary Lecture, followed by a Poster Session highlighting submitted abstracts. Nine ASBMR/Harold M. Frost Young Investigator Awardees will present their work from the podium. A summary of the workshop will be provided through IBMS BoneKEy. Performance Site Sun Valley, Idaho Key Personnel Name Organization Role on Project Burr, David B. Indiana University Director, PI