Studies Toward the Total Synthesis of Leiodelide

描述(由申请人提供)：总体研究计划详细介绍了拟议的有机化学进展调查，以便为制备来碘甲素制定成功的战略。研究设计将解决复杂恶唑合成问题的具体需要。我们将研究新的交叉偶联策略，以具体探索构造跳过的(Z，Pound)-来碘内酯A的二烯所带来的挑战。我们的计划还将探索新的SE‘反应和试剂，以形成具有高立体选择性的关键键。目前还没有关于雷公藤甲素的成功治疗的报道。

DESCRIPTION (provided by applicant): The overall research plan details a proposed investigation of advances in organic chemistry In order to devise a successful strategy for the preparation of leiodelide A. The research design will address specific needs to address problems for the synthesis of complex oxazoles. New cross-coupling strategies will be studied to specifically explore the challenges imposed for construction of the skipped (Z,pound)- diene of leiodelide A. Our plans will also explore new SE' reactions and reagents for the key formation of critical bonds with high stereoselectivity. No reports of successful efforts toward leiodelide A have been published.