RESOURCE CORE 3: BIOSTATISTICS AND DATA MANAGEMENT CORE

生物统计和数据管理核心(RC3)是佛罗里达大学OAIC的四个资源核心之一。UF OAIC的任务是(1)评估老年人身体残疾的危险因素并更好地了解其生物学机制，(2)开发和测试有效的预防疗法，以及(3) 教育和培训新的研究人员在老龄化和残疾方面的研究，同时培养他们的领导素质。生物统计和数据管理核心是来自许多学科的科学家为完成这一任务而相互作用的关键齿轮。核心功能既是数据分析资源，也是数据 协调中心，参与构建数据收集表格和管理数据(包括质量控制)，用于在OAIC内进行研究。在这一能力下，核心维护和更新招聘、遵守和留用核心(RC4)的登记册，并使用网络跟踪系统跟踪审查处内进行的所有研究。核心参与了这些研究的所有阶段，包括初步研究设计和样本量计算、建议前、随机化和数据完成后的最新统计分析。对于目前缺乏方法学的研究设计和数据，核心拥有开发新的最先进方法学的专业知识，以对中心收集的数据进行正确和适当的分析。生物统计和数据管理核心还参与编写手稿，以便在研究界内传播。最后，中心作为研究职业发展核心(RCDC)初级学者的关键资源，提供咨询服务和定期的特殊兴趣培训主题，如研究方法、权力分析、不完整数据分析、数据管理原理和纵向数据分析。

The Biostatistics and Data Management Core (RC3) is one of four resource cores in the OAIC at the University of Florida. The mission ofthe UF OAIC is (1) to assess the risk factors and better understand the biological mechanisms of physical disability in older adults, (2) to develop and test effective prevention therapies, and (3) to educate and train new investigators in research on aging and disability, while developing their leadership qualities. The Biostatistics and Data Management Core is a key cog in the interaction between scientists from many disciplines to accomplish this mission. The core functions as both a data analysis resource and as a data coordinating center, involved in constructing data collection forms and managing the data (including quality control) for the studies conducted within the OAIC. In this capacity, the core maintains and updates the registry for the Recruitment, Adherence, and Retention Core (RC4) and tracks all research conducted within the OAIC with a web tracking system. The core is involved in all phases of these studies including initial study design and sample size calculations pre-proposal, randomization, and state-of-the-art statistical analyses once the data are completed. For study designs and data for which currently methodology is lacking, the core has the expertise to develop new state of the art methodology to perform correct and appropriate analyses of data collected in the Center. The Biostatistics and Data Management Core also is involved in preparation of manuscripts for dissemination within the research community. Finally, the Core serves as a key resource to the Junior Scholars of the Research Career Development Core (RCDC), providing consulting services and periodic special interest training topics, such as research methods, power analysis, analysis of incomplete data, principles of data management, and analysis of longitudinal data.