Baboon Research Resource Program

俄克拉荷马大学健康科学中心(OUHSC)建立了一项狒狒研究 这笔P40赠款、两笔C06建设赠款和一笔R24专用赠款提供了必要的支持 为美国各地的研究人员提供无病原体(SPF)赠款。 我们的使命是立即提供高质量、行为健康的狒狒，并作为 这是一个全国性的生物医学和行为研究资源，需要狒狒参与。狒狒蜂群已经 从P40开始时的141只狒狒成长起来，向506只狒狒提供支持。在过去的时间里 五年来，我们向分布在全国27个机构的外部研究人员提供了452只狒狒 OUHSC SPF计划向美国提供了111只婴儿狒狒。与 俄克拉荷马州立大学兽医健康科学中心和德克萨斯理工大学健康 在科学中心，我们在过去五年里出版了40份同行评议的出版物。这个 出版物是P40支持以资源为基础的研究的结果。发表的文章增加了 了解并增加狒狒作为生物医学研究模型的实用性。这些共同的努力 导致可供研究人员使用和提供给研究人员的狒狒数量增加 同时增加了他们对生物医学研究的几个调查领域的吸引力。 我们继续经历着不仅涉及当地灵长类动物的研究请求的增加，而且 全国范围内。在下一个资助期内，我们建议继续发展和扩展 为了提高我们的能力，以满足不断增长的对非洲的需求 并鼓励非人类灵长类动物的吸引力作为研究模型。为实现这一目标 我们将继续支持对NIH资助的生物医学和行为研究不断增长的需求 在地方、地区和国家一级需要狒狒的方案；2)继续支持发展 OUHSC SPF殖民地；3)更积极地优化成本回收，努力实现自给自足；4) 聘请一名全职博士级别的行为学家与群体合作；以及5)支持基于资源的研究 提高对狒狒模范发展的重视程度。

The University of Oklahoma Health Sciences Center (OUHSC) has established a baboon research resource with the essential support of this P40 grant, two C06 construction grants and a R24 Specific Pathogen Free (SPF) grants that provide baboons for research investigators throughout the United States. Our mission is to provide immediate availability of high quality, behaviorally healthy baboons and to serve as a national resource for biomedical and behavioral research requiring baboons. The baboon colony has grown from 141 baboons at the outset of the P40 grant support to a colony of 506 baboons. Over the past five years we supplied 452 baboons to outside research investigators located at 27 institutions across the United States and 111 infant baboons were supplied to the OUHSC SPF program. Together with the Oklahoma State University Center for Veterinary Health Sciences and the Texas Tech University Health Sciences Center, we have produced 40 peer reviewed publications during the last five years. The publications are the result of the P40 support of resource based research. The published articles add to the knowledge and increase the utility of baboons as models for biomedical research. These combined efforts have resulted in an increase in the number of baboons available for and provided to research investigators along with increasing their attractiveness for several areas of investigation of biomedical research. We continue to experience an increase in research requests involving primates not only locally but nationwide. During the next funding period we propose to continue the development and expansion of the baboon breeding and research programs in order to increase our ability to meet the increased demand for baboons and to encourage the attractiveness of non-human primates as a research model. To meet this goal we will 1) continue to support the increasing demand for NIH funded biomedical and behavioral research programs that require baboons at the local, regional, and national level; 2) continue to support development of the OUHSC SPF colony; 3) more aggressively optimize cost recovery to work towards self-sufficiency; 4) hire a full-time PhD level behaviorist to work with the colony; and 5) support resource based research to improve emphasis on development of the baboon as a model.