Predoctoral Training in Translational Musculoskeletal Research

描述(由申请人提供)：该博士前培训计划的目的是促进优秀的年轻研究人员在翻译肌肉骨骼研究方面的进步。这项重新提交的申请寻求每年四个博士前时段的资金，用于在临床医学和外科以及基础科学和工程学的交叉点进行研究。学员将获得生物工程或材料科学与工程的博士学位，通常为期五年，其中两年由该培训补助金资助。该项目的导师来自加州大学圣地亚哥分校院系的21名资金充足且活跃的教职员工，而加州大学本身以及当地医院和研究机构则提供最先进的研究 实验室和资源。该项目的正规课程课程提供跨学科、创新和严谨的教育体验。学员在两位导师的指导下进行博士研究，一位提供基础科学观点，另一位提供临床观点。这种指导结构将激发一个跨学科的培训环境，有利于在肌肉骨骼翻译方面进行卓有成效的研究和发现。此外，培训计划的主要方面包括：与临床Mentr进行临床轮换，以获得对肌肉骨骼疾病的第一手看法；参加知名会议、职业指导、坚韧不拔的培训，以及生物工程、矫形外科和风湿病等领域的知名演讲者每周举办的研讨会。因此，受训者将在工作台和床边之间发展跨学科的研究技能，使他们能够跳板进入将改善肌肉骨骼疾病和状况的治疗、诊断和预防的职业生涯。 公共卫生相关性：该培训计划将使下一代研究人员具备调查常见肌肉骨骼疾病并提供解决方案的能力和经验。

DESCRIPTION (provided by applicant): The purpose of this Predoctoral Training Program is to facilitate the advancement of outstanding young investigators in Translational Musculoskeletal Research. This resubmission application seeks funding for four predoctoral slots per year to conduct research at the intersection of clinical medicine and surgery and basic science and engineering. The trainees will obtain a Ph.D. degree in Bioengineering or Materials Science and Engineering, typically five years in duration, with two years to be supported by this training grant. Mentorship for the program comes from a core of 21 well-funded and active faculty members in Departments or Divisions at the University of California, San Diego, while the university itself and local hospitals and research institutions offer state of the art research laboratories and resources. The program's formal course curriculum provides an interdisciplinary, innovative and rigorous educational experience. Trainees conduct doctoral research under the guidance of two mentors, one providing a basic science perspective, the other a clinical one. This mentorship structure will stimulate an interdisciplinary training environment conducive to fruitful research and discovery in musculoskeletal translation. Additionally, key aspects of the training program include: a clinical rotation with a clinical mentr in order to obtain a first- hand perspective of musculoskeletal disorders, participation in prominent conferences, career mentorship, training in grantsmanship, and weekly seminars from prominent speakers in fields including bioengineering, orthopaedic surgery and rheumatology. Trainees will thereby develop interdisciplinary research skills, between the bench and bedside, allowing them to springboard to careers that will improve the treatment, diagnosis, and prevention of musculoskeletal diseases and conditions. PUBLIC HEALTH RELEVANCE: This training program will equip the next generation of researchers with the abilities and experiences to investigate and offer solutions to common musculoskeletal disorders.