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中文摘要
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描述(由申请者提供):此会议资助申请将支持2011年12月11日在德克萨斯州休斯敦举行的组织工程和再生医学国际学会北美年会(TERMIS-NA)之前举行的关于“儿科应用的组织工程”的会议前研讨会。目标受众是生物医学科学家、生物工程师和临床医生。组织工程领域的许多研究人员将先天性缺陷和儿童对再生医学的其他需求(以及其他原因)作为他们研究的令人信服的理由。然而,儿科应用实际上只占组织工程领域提出和发表的研究的一小部分,令人惊讶。该讲习班的目的是(I)引起人们对产前、新生儿和儿科患者特殊的组织工程和再生医学需求的关注;(Ii)澄清儿科患者的需求与成人患者的需求有何不同;(Iii)向临床医生(儿科或其他方面)通报本研究的情况,尤其是那些可能不会参加TERMI-NA会议的医生;(Iv)加强儿科临床医生与组织工程研究人员之间的合作并发起讨论;(V)提供一个平台,突出年轻研究人员在儿科组织工程和再生医学领域的研究。为了完成这一使命,我们将以一整天的主题演讲和口头陈述为特色,介绍儿科组织工程应用的研究调查,包括但不限于心血管、骨科、颅面、胃肠和泌尿科。我们将推出一个由临床和基础研究机构不同学术级别的特邀演讲者组成的节目。所有演讲者都参与了儿科临床实践和/或涉及儿科应用的组织工程学的研究。临床医生、生物医学科学家和生物工程师将能够通过技术演示后举行的小组讨论和无数非正式接触的机会来互动和讨论未来的方向。还将在TERMIS-NA主要会议的海报部分专门讨论儿科应用,并将颁发最佳实习生海报奖。受邀发言者名单中有妇女和少数群体的代表,并在会议组织委员会任职。此外,我们将鼓励女性、代表不足的少数族裔或残疾人士参加工作坊,并申请注册折扣。很大一部分与会者将是参加TERMIS-NA年度会议的人,尽管我们也将面向更广泛的受众(地方和国家)。为了提高临床医生的出勤率,我们将在周末举办工作坊。有关工作坊的宣传将包括有关幼儿资源的资料。休斯顿地区,以及德克萨斯儿童医院作为主要机构赞助商的参与,将为拟议的研讨会提供非常强大的科学环境,并有助于评估儿科组织工程的深度、现状和未来挑战。 与公共卫生相关:能够设计可植入的活组织或鼓励组织和器官再生的新技术,为治疗和治愈各种出生缺陷和其他儿童疾病带来了巨大的希望。然而,与成人疗法相比,令人惊讶的是,组织工程研究中只有一小部分专注于儿童患者的需求。这个拟议的研讨会旨在将参与组织工程研究和治疗有组织工程需求的儿科患者的工程师、科学家和临床医生聚集在一起,以推动这些领域的研究并加强合作。
英文摘要
DESCRIPTION (provided by applicant): This Conference Grant application will support a Pre-Conference Workshop on "Tissue Engineering for Pediatric Applications," to be held on December 11, 2011, in advance of the Annual Meeting of Tissue Engineering and Regenerative Medicine International Society - North America (TERMIS-NA) in Houston, TX. The target audience is biomedical scientists, bioengineers, and clinicians. Many investigators in the field of tissue engineering cite congenital defects and other needs for regenerative medicine in children (among other reasons) as compelling justification for their research. However, pediatric applications actually represent a surprisingly small fraction of research presented and published in the tissue engineering field. The mission of this workshop is (i) to draw attention to the specific tissue engineering and regenerative medicine needs of prenatal, neonatal, and pediatric patients; (ii) to clarify how needs for pediatric patients differ from the needs of adult patients; (iii) to inform clinicians (pediatric or otherwise) about this research, especially those who might not otherwise attend the TERMIS-NA conference; (iv) to enhance collaboration and initiate discussions between pediatric clinicians and tissue engineering researchers; and (v) to provide a platform to highlight the research of young investigators in the field of pediatric tissue engineering and regenerative medicine. To accomplish this mission, we will feature a full day of keynote lectures and oral presentations describing research investigations on pediatric tissue engineering applications including but not limited to cardiovascular, orthopedic, craniofacial, gastrointestinal, and urological. We will feature a program of invited speakers at various academic ranks from clinical and basic research institutions. All of the speakers are involved in pediatric clinical practice and/or research involving tissue engineering for pediatric applications. Clinicians, biomedical scientists, and bioengineers will be able to interact and discuss future directions through panels held after the technical presentations and numerous opportunities for informal engagement. There will also be a section of the poster session of the main TERMIS-NA conference dedicated to pediatric applications, and awards for best trainee posters will be given. Women and minorities are represented in the list of invited speakers and serve on the conference organizing committee. In addition, we will encourage trainees and faculty who are women, under-represented minorities, or persons with disabilities to attend the workshop and apply for registration discounts. A significant portion of the attendees will be persons also attending the annual TERMIS-NA conference, although we will also target a broader audience (locally and nationally). To promote attendance by clinicians, we will hold the workshop on the weekend. Publicity about the workshop will include information about child care resources. The Houston locale, and the involvement of Texas Children's Hospital as the primary institutional sponsor, will provide a very strong scientific environment for the proposed workshop and facilitate evaluation of the depth, current status, and future challenges in pediatric tissue engineering. PUBLIC HEALTH RELEVANCE: New technologies with the ability to engineer implantable living tissues or encourage the regeneration of tissues and organs hold great promise for the treatment and cure of a variety of birth defects and other childhood afflictions. However, a surprisingly small fraction of tissue engineering research focuses on the needs of pediatric patients when compared to adult therapies. This proposed workshop aims to bring together engineers, scientists and clinicians involved in tissue engineering research and in treating pediatric patients with tissue engineering needs in order to motivate research in these areas and enhance collaboration.
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Differential Shear Forces on Endocardial Endothelial Cells Regulate a Fibrotic Spectrum in the Left Ventricular Outflow Tract
  • 批准号:
    10170409
  • 项目类别:
  • 资助金额:
    $52.07万
  • 财政年份:
    2018
  • 负责人:
    KATHRYN JANE GRANDE-ALLEN
  • 依托单位:
Engineering MicroEnvironment Core (EMEC)
  • 批准号:
    10192207
  • 项目类别:
  • 资助金额:
    $16.85万
  • 财政年份:
    2015
  • 负责人:
    KATHRYN JANE GRANDE-ALLEN
  • 依托单位:
Engineering MicroEnvironment Core (EMEC)
  • 批准号:
    10642942
  • 项目类别:
  • 资助金额:
    $20.19万
  • 财政年份:
    2015
  • 负责人:
    KATHRYN JANE GRANDE-ALLEN
  • 依托单位:
Engineering MicroEnvironment Core (EMEC)
  • 批准号:
    10462790
  • 项目类别:
  • 资助金额:
    $16.51万
  • 财政年份:
    2015
  • 负责人:
    KATHRYN JANE GRANDE-ALLEN
  • 依托单位:
海外基金