Sun Valley Workshop: Musculoskeletal Biology

描述（由申请人提供）： 本申请请求支持2011年8月5日至8日在爱达荷州太阳谷举行的Skeleton生物学太阳谷研讨会年会。太阳谷研讨会有40年的传统，是为了向年轻科学家提供多学科培训。讲习班继续强调青年教师和学生的积极参与。研讨会成功地促进了跨学科交流，并且不同寻常的是，讨论时间等于或超过了正式演讲的时间。该讲习班的目标是：（1）努力实现与骨关节疾病的发病机制、预防和治疗有关的分子、组织和生物力学过程的多学科基础和临床综合;（2）在基础和临床研究人员之间开展对话;（3）为初级教师和学生提供培训讲习班，帮助弥合学科之间的差距;（4）为学生提供培训平台，并让初级研究人员有机会在小组环境中与较资深的科学家交谈。研讨会与国际骨与矿物学会（IBMS）之间的合作关系改善了营销，特别是在国际上，并通过IBMS BoneKEy广播电子邮件和IBMS网站上的链接提供了最大的知名度。第42届太阳谷研讨会聚焦于两个主题。三个会议将探讨机械生物学的发展，组织再生，和炎性小体（通过假体植入物周围重塑）。研讨会将以针对糖皮质激素诱导的骨质疏松症和骨细胞生理学的骨质量会议为基础。初级调查员有许多机会与高级调查员进行互动。星期天晚上的会议是预留给全体讲座，其次是海报会议突出提交的摘要。9 ASBMR/Harold M.弗罗斯特青年研究员获奖者将在讲台上展示他们的工作。计划利用网上资源和通过在BoneKEy上发表来宣传和分发讲习班摘要。表演场地太阳谷，爱达荷州 公共卫生相关性：该研讨会与公共卫生问题有关，因为它汇集了多学科的高级和初级科学家，共同讨论改善肢体再生，假体周围植入成功的新策略，以及使用干细胞治疗各种肌肉骨骼损伤或发育异常。糖皮质激素性骨质疏松症的发病机制和治疗也将进行讨论。该讲习班向可能不完全熟悉这些公共卫生问题疾病的所有方面的从业人员和科学家提供从基础科学到临床病理学的纵向信息。

DESCRIPTION (provided by applicant): This application requests support for the annual meeting of the Sun Valley Workshop on Skeletal Biology held in Sun Valley, Idaho, August 5-8, 2011. The Sun Valley Workshops have a 40 year tradition that grew out of an attempt to provide multidisciplinary training to younger scientists. The Workshops continue to emphasize active participation of junior faculty and students. The Workshops have been successful in promoting interdisciplinary communication, and are unusual in that discussion time equals or exceeds time allotted for formal presentation. The goals of the Workshop are to (1) work toward a multidisciplinary basic and clinical synthesis of molecular, tissue and biomechanical processes related to the pathogenesis, prevention and treatment of bone and joint diseases; (2) develop a dialogue between basic and clinical investigators; (3) provide training workshops for junior faculty and students that help bridge the gaps between disciplines; (4) provide a forum for student training and the opportunity for junior investigators to talk with more senior scientists i a small group setting. A partnership between the Workshop and the International Bone and Mineral Society (IBMS) has improved marketing, especially internationally, and provides maximum visibility through IBMS BoneKEy broadcast emails and links on the IBMS website. The 42nd Sun Valley Workshop is focused on two themes. Three sessions will explore the mechanobiology of development, tissue regeneration, and the inflammasome (through peri-prosthetic implant remodeling). The Workshop will be anchored by sessions on bone quality that target glucocorticoid-induced osteoporosis, and osteocyte physiology. Numerous opportunities are provided for junior investigators to interact with more senior investigators. The Sunday evening session is set aside for a Plenary Lecture, followed by a Poster Session highlighting submitted abstracts. Nine ASBMR/Harold M. Frost Young Investigator Awardees will present their work from the podium. There are plans to advertise and distribute a summary of the workshop using Web-based resources and through publication in BoneKEy. Performance Site Sun Valley, Idaho PUBLIC HEALTH RELEVANCE: This Workshop is relevant to public health concerns because it brings a multi-disciplinary group of senior and junior scientists together to discuss new strategies to improve limb regeneration, periprosthetic implant success, and the use of stem cells to treat a variety of musculoskeletal injuries or developmental anomalies. The pathogenesis and treatment of glucocorticoid-induced osteoporosis will also be discussed. The Workshop provides vertically-oriented information, from the basic science to clinical pathology, to practitioners and scientists who may not be completely familiar with all aspects of these diseases of public health concern.