DRP: Developmental Research Program

前列腺孢子发育研究计划在行政核心的指导下运作。SPORE每年拨出150，000美元（加上机构支持）资助4-5个可行性项目，以生成数据，使研究人员能够申请校外资金。每年一月，西北大学和芝加哥大学癌症中心的所有成员都会收到试点项目的申请。有一个由特设审查委员会对试点项目进行同行审查的既定程序。 SPORE执行委员会优先考虑分数，并做出最终的资金决定。这一过程是灵活的，因为试点项目可以升级，以取代完整的SPORE项目，如果进展不令人满意，试点项目可以终止。例如，项目4（PI：Bergan和Catalona）和项目3（PI： Weichselbaum和Stadler）都是试点项目， 取得了重大进展。项目2（PI：Crawford，Gapstur和Lee）也从试点项目升级。此外，研究者可随时向SPORE主任提交试点项目。它由特设委员会审查，如果审查结果良好，并且有足够的资金，它可能会得到资助。因此，发展研究计划使前列腺孢子扩大研究者的参与，使更多的研究者进入该领域，以最大限度地提高我们对前列腺癌的研究工作。申请书第十二节详细介绍了试点项目

The Prostate SPORE Developmental Research Program operates under the direction of the Administrative Core. The SPORE sets aside $150,000 each year (plus Institutional support) to fund 4-5 feasibility projects to generate data that will enable the investigator to apply for extramural funds. In January of each year a request for pilot projects is sent out to all members of the Cancer Centers at Northwestern University and the University of Chicago. There is an established process for peer review of pilot projects by an ad hoc review committee. The SPORE Executive Committee takes priority scores and makes the final funding decision. The process is flexible, in that pilot projects can be elevated to replace full SPORE projects and pilot projects can be terminated if progress is not satisfactory. For example, Project 4 (PI: Bergan and Catalona) and Project 3 (PI: Weichselbaum and Stadler) were both pilot projects that were elevated to full project status based on significant progress made. And Project 2 (PI: Crawford, Gapstur and Lee) has also been elevated from a pilot project. Additionally, an investigator may submit a pilot project at any time to the SPORE Director. It is reviewed by the ad hoc committee and if favorably reviewed and if adequate funds exist, it may receive funding. Therefore, the Developmental Research Program enables the Prostate SPORE to expand investigator participation to bring more investigators into the field to maximize our research efforts on prostate cancer. A detailed description of pilot projects is described in Section XII of the application