BD2K Consortium Activities

大数据生物医学知识因果建模和发现中心（CCMD）的联盟活动组件（CAC）将确保匹兹堡中心参与并整合到所有BD2K中心联盟活动中。在生物医学信息学、计算和系统生物学、哲学、计算机科学、超级计算、统计遗传学、癌症研究、功能磁共振成像和肺部疾病等领域，我们的CCMD团队将成为数据科学、生物医学等许多学科的广泛接口。作为联盟的一部分，CCMD将为实现以下BD2K目标做出贡献：1)通过联盟传播CCMD开发的数据和工具；2)通过与其他联盟站点的合作，扩展数据和软件共享政策和实践；3)开发与其他联盟站点集成的大数据分析新方法，例如与哈佛大学的Intra-Consortium Project 1；4)使用基于标准的元数据来描述CCMD工具所使用的数据，例如在与斯坦福大学的Intra-Consortium Project 2中提出的数据。我们实现这些目标的部分方法将是部署技术催化剂，其主要职责将是花时间与其他资助的财团站点一起学习。该个人的主要职责是提供CCMD技术更新，描述在对其他受资助的BD2K中心进行季度轮换实地考察后，CCMD集成和互操作性将如何完成。作为我们对BD2K联盟承诺的一部分，CCMD将参加联盟的所有会议和联盟的所有小组委员会，如数据共享、出版、监管、评估以及指导委员会创建的其他会议。我们将参与制定并遵守这些委员会制定的所有政策。通过这个CCMD组件，我们将为BD2K作为其中心目标的研究文化的改变做出贡献。

The Consortium Activities Component (CAC) of the Center for Causal Modeling and Discovery (CCMD) of Biomedical Knowledge from Big Data will ensure the Pittsburgh Center's participation and integration into all of the BD2K Center Consortium Activities. With highly collaborative leaders in the fields biomedical informatics, computational and systems biology, philosophy, computer science, supercomputing, statistical genetics, cancer research, fMRI, and lung disease, our CCMD team will serve as a broad interface into many disciplines in data science, biomedicine, and beyond. As part of the Consortium, CCMD will contribute to the achievement of the following BD2K goals: 1) Disseminate data and tools developed by the CCMD through the Consortium; 2) Extend data- and software-sharing policies and practices through collaboration with other Consortium sites; 3) Develop new methods to analyze big data that integrate with other Consortium sites, such as those proposed in Intra-Consortium Project 1 with Harvard; and 4) Use standards-based metadata to describe the data consumed by the tools of CCMD, such as those proposed in Intra-Consortium Project 2 with Stanford. Part of our approach to achieving these goals will be the deployment of a Technical Catalyst whose main responsibility will be to spend time learning with and from the other funded consortium sites. A key responsibility for this individual will be the production of CCMD technical updates describing how CCMD integration and interoperability will be accomplished after careful study during quarterly, rotating site visits of the other funded BD2K Centers. As part of our commitment to the BD2K Consortium, the CCMD will participate in all Consortium meetings and in all of the Consortium subcommittees, such as data sharing, publication, regulatory, evaluation, and others created by the Steering Committee. We will participate in the development of and abide by all policies set by these committees. Through this CCMD component, we will contribute to the change in research culture that BD2K has as its central goal.