PS09-007, Evaluating Locally-Developed Homegrown HIV Prevention Interventions

描述（由申请人提供）：美国东南部拥有该国增长最快的拉丁裔人口，同时也承担着不成比例的艾滋病毒负担。针对拉丁裔或男男性行为者（MSM）的有效艾滋病毒预防干预措施很少。为了响应RFA-PS-09-007“评估非洲裔美国人和西班牙裔/拉丁裔男同性恋者本地开发的（本土）艾滋病毒预防干预措施”，我们的社区大学合作伙伴提出了一项为期5年的研究（U01），以加强、全面实施和严格评估旨在增加拉丁裔男同性恋者安全套使用和艾滋病毒检测的小组干预措施。干预措施是由查塔姆社会卫生理事会工作人员和社区合作伙伴，包括拉丁裔男同性恋者制定的，并以社会认知理论和赋权教育理论为基础。这项拟议的研究是社区大学长期合作的结果。总共有300名拉丁裔男同性恋者将被招募。参与者将完成最初的基线风险行为评估，旨在衡量当前的性行为，以及心理、社会和文化对性行为和医疗保健使用的影响。然后，参与者将被随机分配到一个4期的艾滋病预防小组干预（HOLA en Grupos）或一个4期的癌症预防教育小组比较干预。所有参与者也将在3个月和12个月的随访中完成相同的评估。艾滋病毒预防干预的参与者，相对于对照组的同龄人，预计会证明(a)在性交过程中增加了自我报告使用避孕套的情况；(b)自我报告使用艾滋病毒和性传播疾病咨询、检测和治疗服务的人数增加；(c)更多地了解艾滋病毒对社区（包括拉丁裔和男同性恋者）的影响，以及艾滋病毒风险行为和预防策略；(d)对禁欲和使用避孕套持更积极的态度；(e)提高使用和坚持使用避孕套的自我效能；(f)掌握感得分提高；(g)减少减少风险的障碍（例如，男子气概损害健康的方面）；(h)提高伴侣和提供者的沟通和性谈判技巧。这项研究的结果和成果将被传播，为公共卫生实践、研究和政策提供信息。结果和产品将包括：(1)与文化相关的西班牙语干预；旨在减少拉丁裔男男性行为者的艾滋病毒风险，并准备传播；(2)加深对拉丁裔男同性恋者艾滋病毒风险和干预的认识。

DESCRIPTION (provided by applicant): The Southeastern United States has the fastest-growing Latino population in the country and at the same time carries a disproportionate HIV burden. Few efficacious HIV prevention interventions exist for either Latinos or men who have sex with men (MSM). In response to RFA-PS-09-007 "Evaluating Locally-Developed (Homegrown) HIV Prevention Interventions for African American and Hispanic/Latino MSM," our community-university partnership proposes a 5-year study (U01) to enhance, fully implement, and rigorously evaluate a small-group intervention designed to increase condom use and HIV testing among Latino MSM. The intervention was developed by Chatham Social Health Council staff and community partners, including Latino MSM, and is based on social cognitive theory and theory of empowerment education. The proposed study is a result of a long-term community-university partnership. A total of 300 Latino MSM will be enrolled. Participants will complete an initial baseline risk behavior assessment designed to measure current sexual behavior, and psychological, social, and cultural influences on sexual behavior and healthcare use. Participants then will be randomized to a 4-session small-group HIV prevention intervention (HOLA en Grupos) or a 4-session small-group cancer prevention education comparison intervention. All participants also will complete identical assessments at 3-month and 12-month follow-up. Participants in the HIV prevention intervention, relative to their peers in the comparison group, are anticipated to demonstrate (a) increased self-reported use of condoms during sexual intercourse; (b) increased self-reported use of HIV and sexually transmitted disease (STD) counseling, testing, and treatment services; (c) greater knowledge of the impact of HIV on communities (including Latino and MSM), and HIV risk behaviors and prevention strategies; (d) more positive attitudes towards abstinence and condom use; (e) increased self- efficacy to use and assert the use of condoms; (f) increased sense of mastery scores; (g) decreased barriers to risk reduction (e.g., health-compromising aspects of machismo); and (h) enhanced partner and provider communication and sexual negotiation skills. The results and products from this study will be disseminated to inform public health practice, research, and policy. Results and products will include: (1) a Spanish-language intervention that is: culturally relevant; designed to reduce HIV risk among Latino MSM, and ready for dissemination; and (2) a deeper understanding of HIV risk and intervention among Latino MSM.