Tulane Building Interdisciplinary Research Careers in Women's Health (BIRCWH)

描述（由申请人提供）：这是杜兰大学BIRCWH项目的竞争更新申请，该项目在过去的4年里成功地培养了一批种族/民族和专业多样化的跨学科研究人员，提高了杜兰大学对妇女健康研究的认识。我们现在建议在之前成功的基础上，扩大和加强BIRCWH项目基础。长期目标是增加妇女健康领域训练有素、有文化能力、独立、跨学科研究人员的数量和多样性，重点是心血管疾病及相关疾病领域的性别差异研究。该项目专注于心血管疾病及相关疾病，因为心脏病对女性的影响、心血管疾病在研究领域的性别差异方面的现有知识差距，以及杜兰大学这方面的优势。我们成功的职业发展计划的关键组成部分包括：1)针对学者的具体需求量身定制的教学课程；2)个性化职业发展培训；3) BIRCWH系列讲座；4)正在进行的会议；5)所需的拨款撰写和项目管理研讨会；6)指导跨学科研究；7)在科研培训中负责任。创新的方法包括通过两个职业发展轨道（轨道1适用于研究经验有限的学者；轨道2适用于具有先前研究经验的学者）来根据学者的需求定制项目，并为每位学者使用网络指导模式，包括基础科学和临床研究方面的专业知识。学者们立即接触到研究，并被引导尽早建立学术记录，并通过积极参与妇女健康研究日获得演讲和组织技能。增强后的BIRCWH项目的新组成部分包括增加教师对新学科的参与，通过网络指导增加基础科学家和临床研究人员之间的跨学科互动，加强与Xavier（一个历史悠久的黑人，研究密集型较低的机构）的合作，以及增加对机构资源的获取。这些学者将学习前沿的研究方法和技能，从Bench（细胞、分子和遗传学）到床边（临床研究和临床试验）到人口（流行病学、预防和卫生服务研究），并在一个有指导的跨学科环境中，在已建立的实验室/研究小组中开展自己的研究项目，以解决ORWH最新的优先事项。学者的跨学科研究活动将侧重于心血管疾病和相关疾病的性别差异及其风险因素，并解决总体主题（寿命、性别/性别决定因素、健康差异和跨学科研究）。我们建议培养8名教师学者，至少2-3年（医生科学家至少3年）。持续和全面的评估将指导改进该项目在桥梁研究培训和研究独立性方面的有效性，为专注于性别差异和心血管疾病的初级研究人员提供帮助。

DESCRIPTION (provided by applicant): This is a competing renewal application for the Tulane BIRCWH Program, which has successfully trained a racially/ethnically and professionally diverse group of interdisciplinary researchers in women's health and increased awareness of women's health research at Tulane over the last 4 years. We propose now to build on our prior success and expand and reinforce the BIRCWH program base. The long-term goal is to increase the number and diversity of highly trained culturally competent, independent, interdisciplinary investigators in Women's Health with an emphasis on Sex Differences research in the field of cardiovascular disease (CVD) and related diseases. The program focuses on CVD and related diseases because of the impacts of heart dis- ease on women, the existing knowledge gaps on the sex differences in CVD across the research spectrum, and the strength of this focus at Tulane. Key components of our successful career development plan include 1) didactic courses tailored to specific Scholar needs; 2) individualized career development training; 3) BIRCWH seminar series; 4) Work-in-Progress sessions; 5) required grant writing and project management workshops; 6) mentored interdisciplinary research; and 7) responsible conduct in research training. The innovative approach includes tailoring the program to Scholars needs via 2 career development tracks (Track 1 for Scholars with limited research experience; Track 2 for Scholars with prior research experience), and using a network mentoring model for each Scholar, including expertise in both basic science and clinical research. Scholars are immediately exposed to research and are guided to establish a scholarly track record early, and gain presentation and organization skills by active participation in the Women's Health Research day. New components of the enhanced BIRCWH program include additional faculty participation in new disciplines, in- creased interdisciplinary interactions between basic scientists and clinical researchers through network mentoring, strengthened collaboration with Xavier, a historically Black, less-research-intensive institution, and enhanced access to institutional resources. The Scholars will learn cutting-edge research methods and skills from Bench (cellular, molecular, and genetics), to Bedside (clinical research and clinical trials) to Population (epidemiology, prevention, and health services research) and conduct their own research projects in established laboratories/research groups in a mentored, interdisciplinary environment that address the most recent ORWH priorities. Scholar's interdisciplinary research activities will focus on sex differences in CVD and related diseases and their risk factors and address overarching themes (lifespan, sex/gender determinants, health disparities, and interdisciplinary research). We propose to train 8 faculty Scholars for a minimum of 2-3 years (3 years minimum for physician-scientists). Ongoing and comprehensive evaluation will guide improvements to the program's demonstrated effectiveness in bridging research training and research independence for junior investigators focused on Sex Differences and CVD.