Interdisciplinary and Translational Research Training in NeuroAIDS

描述（由申请人提供）：此修订后的竞争性续期申请提供了一个计划，用于继续和进一步发展“NeuroAIDS跨学科和转化研究培训计划（ITRTP）”，用于研究HIV感染的中枢神经系统并发症和相关研究领域的博士生。这是一个联合计划，从两个机构，天普大学和德雷克塞尔大学，位于宾夕法尼亚州费城附近。该计划还整合了培训活动和研究资源，可在综合中心NeuroAIDS（CNAC）涉及寺和德雷克塞尔大学以及长期的MD/博士和临床研究培训计划在艾滋病和神经病毒学的基础上在神经病学系，艾滋病研究中心（CFAR）在宾夕法尼亚大学。我们正在进行的计划通过共享资源，联合研讨会，研讨会，专题讨论会，特邀演讲者以及两个机构的论文指导和教育活动，进一步发展了全市范围内的神经艾滋病跨学科和转化研究培训计划。这两个机构的研究生课程旨在为生物医学科学提供广泛的科学基础，包括神经科学，免疫学，微生物学，药理学和生理学。该课程包括负责任的研究，科学交流，统计学，以及在分子和细胞神经生物学，神经发病机制和转化神经科学深入培训的高级课程。该计划汇集了多个生物医学基础科学部门，并与附近的宾夕法尼亚大学的两个机构整合了联合培训活动。随着临床艾滋病调查人员的加入，以及CNAC核心设施，我们的培训计划不仅是跨学科的，而且让学生接触到基础科学和临床观点，重点是艾滋病毒/艾滋病/神经艾滋病。我们的联合培训计划，加上我们的联合基础设施资源，通过我们的CNAC和附近的宾夕法尼亚大学CFAR，提供了一个强大的，互动的，非常成功的培训环境在大费城地区的神经病毒学和神经艾滋病。为了支持和加强我们的代表性不足的少数民族在此程序中的招聘，此应用程序现在包括本科生和医科学生的暑期实验室培训，将提供进入我们的博士和MD/PhD NeuroAIDS培训计划的途径提供。

DESCRIPTION (provided by applicant): This revised competing renewal application provides a plan for the continuation and further development of the "Interdisciplinary and Translational Research Training Program (ITRTP) in NeuroAIDS" for predoctoral students studying central nervous system complications of HIV infection and related areas of research. This is a joint program from two institutions, Temple University and Drexel University, located in close proximity in Philadelphia, Pennsylvania. This program also integrates training activities and research resources available in the Comprehensive Center for NeuroAIDS (CNAC) involving both Temple and Drexel University as well as long-standing MD/PhD and clinical research training programs in AIDS and Neurovirology based in the Department of Neurology, and Center for AIDS Research (CFAR) at the University of Pennsylvania. Our ongoing program further develops a citywide interdisciplinary and translational research training program in NeuroAIDS through shared resources, joint seminars, workshops, symposia, invited speakers, as well as thesis mentoring and educational activities at both institutions. The graduate curriculum at both institutions is designed to provide a broad based scientific foundation in biomedical sciences, including neuroscience, immunology, microbiology, and pharmacology and physiology. This curriculum includes responsible conduct of research, scientific communication, statistics, as well as advanced courses with in- depth training in molecular and cellular neurobiology, neuropathogenesis, and translational neuroscience. This program brings together multiple biomedical basic science departments and integrates joint training activities at two institutions with nearby University of Pennsylvania. With the inclusion of clinical AIDS investigators, as well as CNAC Core facilities, our training program is not only interdisciplinary, but exposes students to basic sciences and clinical perspectives focusing on HIV/AIDS/NeuroAIDS. Our joint training program, together with our joint infrastructural resources available through our CNAC and the nearby University of Pennsylvania CFAR, provides a strong, interactive, and highly successful training environment in neurovirology and NeuroAIDS within the greater Philadelphia region. In order to support and enhance our under-represented minority recruitment within this program, this application now includes the provision for summer laboratory training of undergraduates and medical students that would provide pathways for entry into our PhD and MD/PhD training program in NeuroAIDS.