Interdisciplinary and Translational Research Training in NeuroAIDS

描述（由申请人提供）：本申请提供了一个跨学科和转化研究培训计划（ITRTP）的计划，为神经艾滋病和相关研究领域的博士前学生。这是一个联合计划，从两个机构，天普大学和德雷克塞尔大学，位于靠近费城，宾夕法尼亚州。该计划还将整合培训活动和研究资源，可在一个长期倾向的医学博士/博士以及宾夕法尼亚大学神经病学系的艾滋病和神经病毒学临床研究培训项目。拟议的计划将通过共享资源，联合研究研讨会系列，期刊俱乐部，专题讨论会，特邀演讲者，论文指导和两个机构的教育机会，在NeuroAIDS中创建一个全市范围的跨学科和转化研究培训计划。这两个机构的研究生课程旨在为生物医学科学提供广泛的科学基础，包括神经科学，免疫学，微生物学，药理学和生理学。该课程包括科学交流，科学诚信和生物伦理学，统计学，以及分子和细胞神经生物学和神经生物学疾病发病机制课程将为NeuroAIDS的论文研究做好准备。在坦普尔大学医学院内，神经科学系，微生物学和免疫学系，药理学系和生理学系提供神经艾滋病和相关领域的研究机会。其他研究机会可在工程学院。在德雷克塞尔大学医学院，在神经艾滋病和相关领域的研究机会可在微生物学和免疫学系，神经生物学和解剖学系，药理学和生理学系以及生物化学和分子生物学系。生物医学工程和健康科学系统学院提供额外的研究机会。该计划汇集了两个机构的多个生物医学基础科学部门与生物医学工程，并与附近的宾夕法尼亚大学整合了联合培训活动。随着临床艾滋病调查人员的加入，拟议的计划不仅是跨学科的，但暴露学生在neuroAIDS基础科学培训艾滋病和neuroAIDS相关的临床观点。Temple和Drexel的研究人员已经建立了强大，富有成效和资金充足的NeuroAIDS研究计划，这些计划现已充分建立，以支持NeuroAIDS的正式全面培训，范围包括分子研究，体外系统和人类和非人类的发病机制研究。

DESCRIPTION (provided by applicant): This application provides a plan for an Interdisciplinary and Translational Research Training Program (ITRTP) for predoctoral students in NeuroAIDS and related areas of research. This is a joint program from two institutions, Temple University and Drexel University, located in close proximity in Philadelphia, 'Pennsylvania. This program will also integrate training activities and research resources available in a long- tending M.D./Ph.D. and clinical research training programs in AIDS and Neurovirology based in the Department of Neurology, University of Pennsylvania. The proposed plan will create a city-wide interdisciplinary and translational research training program in NeuroAIDS through shared resources, joint research seminar series, journal club, symposia, invited speakers, thesis mentoring and educational opportunities at both institutions. The graduate curriculum at both institutions is designed to provide a broad based scientific foundation in biomedical science including Neuroscience, Immunology, Microbiology, Pharmacology and Physiology. This curriculum including Scientific Communication, Scientific Integrity and Bioethics, and Statistics, as well as courses in Molecular and Cellular Neurobiology and Pathogenesis of Neurobiological Diseases will prepare graduate student for thesis research in NeuroAIDS. Within Temple University School of Medicine, research opportunities in NeuroAIDS and related areas are available within the Department of Neuroscience, Department of Microbiology and Immunology, Department of Pharmacology, and Department of Physiology. Additional research opportunity is available in the School of Engineering. At Drexel University College of Medicine, research opportunities in NeuroAIDS and related areas are available in the Department of Microbiology and Immunology, Department of Neurobiology and Anatomy, Department of Pharmacology and Physiology and Department of Biochemistry and Molecular Biology. Additional research opportunities are available in the School of Biomedical Engineering and Health Science Systems. This program brings together multiple biomedical basic science departments with biomedical engineering at two institutions, and integrates joint training activities with nearby University of Pennsylvania. With the inclusion of clinical AIDS investigators, the proposed program is not only interdisciplinary, but exposes students to training in neuroAIDS basic sciences to AIDS and NeuroAIDS related clinical perspectives. Investigators at Temple and Drexel have built strong, productive and well-funded NeuroAIDS research programs that are now sufficiently established to support formal comprehensive training in NeuroAIDS in areas ranging from molecular studies, in vitro systems, and pathogenesis studies in human and non-human.