Applications of methods in collaborative science

在与NIEHS早孕研究相关的工作中，我们有一篇正在修订的论文，该论文考虑了与双酚A和邻苯二甲酸酯水平相关的生育力，早孕丢失和月经周期特征，如EPS中收集的每日尿液样本所测量的。NHANES项目基本上是负面的，只有一个例外是男性中的三氯生，这与抗核抗体的存在密切相关。 那篇论文已经快要提交了。在另一个基于NHANES数据和ANA的项目中，发现女性的生育史与ANA的患病率相关，而产次与这种自身免疫生物标志物的患病率较高相关。目前正在开始一项由国防部资助的研究，研究军事人员在服兵役期间所经历的暴露与自身免疫性疾病肌炎的关系。 该项目的PI是Fred米勒（NIEHS）。我们与卑尔根大学和挪威医学出生登记处合作开展了另一系列项目。我们已经分析了季节对挪威早产的影响，并准备提交一篇论文，我们已经开始分析季节与先兆子痫的关系。

In work related to the NIEHS Early Pregnancy Study we have a paper under revision that considers fertility, early pregnancy loss and menstrual cycle characteristics in relation to levels of bisphenol A and phthalates, as measured in the daily urine samples collected in the EPS. The NHANES project was largely negative, with the one exception being triclosan in males, which was strongly related to the presence of antinuclear antibodies. That paper is very close to ready for submission. In another project based on NHANES data and ANA reproductive history in women was found to be related to the prevalence of ANA, with parity being associated with higher prevalence of this autoimmunity biomarker. Collaborative work is now beginning on a DoD-funded study of the auto-immune disease myositis in military personnel in relation to exposures experienced during their years of military service. The PI on this project is Fred Miller (NIEHS). We have another set of projects based on collaboration with the University of Bergen and the Medical Birth Registry of Norway. We have analyzed seasonal effects on preterm birth in Norway and have a paper almost ready to submit, and we have begun analysis of season in relation to preeclampsia.