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中文摘要
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描述(由申请者提供):这项提案是对慢性非传染性疾病和非传染性疾病在生命周期内的Fogarty倡议的回应,重点关注印度三个正在经历城市化严重有害影响的地点:印度东北部(阿萨姆邦和锡金邦)和印度中南部(卡纳塔克邦)。Fogarty提交的这份报告的目标与Fogarty战略计划保持一致,目的是缩小CNCDs的培训差距并提高研究能力,并重点关注那些在中低收入国家(LMIC)日益加重疾病负担但很少受到关注的行为状况。该方案涉及暴力、成瘾(处方药和非法药物、酒精和尼古丁)以及最具破坏性的精神症状(精神病、自杀意念和痴呆症)。它还强调对疾病的社会决定因素(环境和社会因素)以及表观遗传决定因素的培训。这一新计划将加强和扩大通过落日的Fogarty ICOHRTA计划开展的工作,该计划自2001年以来得到资助,由华盛顿大学的Linda Cottler博士和印度卡纳塔克邦班加罗尔国家心理健康和神经科学研究所(NIMHANS)的主要外国合作者Sanjeev Jain博士领导。在CNCD机制下,我们正在增加两个新的机构,特别是阿萨姆邦Tezpur的Lokopya Gopinath Bordoloi(LGBRIMH)区域精神卫生研究所和锡金甘托克自愿卫生协会(VHAS)。增加这些项目是为了加强我们与主要非政府组织机构合作的培训的公共卫生和政策重点。印美团队已经在与班加罗尔NIMHANS培训的精神卫生专业人员以及吴的精神病学系合作的精神卫生专业人员的研究能力建设方面取得了相当大的进展;这一新的Fogarty使吴和NIMHANS有机会继续建设所需的公共卫生相关研究能力,同时也连接到锡金和阿萨姆邦的东北部地区-这些地区迫切需要可持续的研究能力建设和外展指导。我们建议每年培训4名长期实习生--2名博士后和2名博士后--为期5年。培训咨询小组(TAG)将对受训人员的选择和进展情况进行评估,该小组将就与印度培训讲习班的重点有关的问题向主任和主要外国合作者提供反馈,并就各机构之间和各机构之间更多合作赠款的想法提供反馈。该计划的学员将有机会参加正式课程,参加研讨会和教程,并与他们的导师一起学徒式的工作。负责任的研究行为培训是这个项目的一个主要重点。通过我们的三个印度站点的扩展计划,一个增加了容量,两个迫切需要基础设施建设,以及我们新的重点网络,我们将发展可持续的合作伙伴关系,以应对世界上一些最沉重的慢性传染性疾病。
英文摘要
DESCRIPTION (provided by applicant): This proposal, responding to the Chronic Non-Communicable Diseases and Disorders Across the Lifespan (CNCD) Fogarty initiative, focuses on three locations in India that are experiencing acute, detrimental effects of urbanization: Northeast India (Assam and Sikkim) and South Central India (Karnataka). The goals of this Fogarty submission align with the Fogarty Strategic Plan to reduce the training gap and increase research capacity for CNCDs, and focuses on behavioral conditions that receive little attention even though they are increasingly contributing to the burden of disease in Lower and Middle Income Countries (LMICs). This program addresses exposure to violence, addiction (prescribed and illicit drugs, alcohol and nicotine), and the most impairing mental symptoms (psychosis, suicidal ideation and dementia). It also emphasizes training in the social determinants of illness (environmental and social factors), as well as epigenetic determinants, across the lifespan. This new program will enhance and expand the work conducted through a sunsetted Fogarty ICOHRTA Program, funded since 2001, directed by Dr. Linda Cottler from Washington University and Major Foreign Collaborator Dr. Sanjeev Jain from the National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, Karnataka, India. Under the CNCD mechanism, we are adding two new institutions, specifically, Lokopriya Gopinath Bordoloi (LGBRIMH) Regional Institute of Mental Health in Tezpur, Assam and the Voluntary Health Association of Gangtok, Sikkim (VHAS). These programs are added to increase the public health and policy emphasis of our training collaborating with premier NGO institutions. The INDO-US team has already made considerable progress building research capacity with mental health professionals trained by NIMHANS in Bangalore paired with WU's Department of Psychiatry; this new Fogarty gives WU and NIMHANS the opportunity to continue building needed public health relevant research capacity while also bridging to Northeast areas of Sikkim and Assam-areas that have critical need for sustainable research capacity building and outreach mentoring. We propose to train 4 long term trainees-2 pre docs and 2 post docs-every year for 5 years. Trainee selection and progress will be evaluated by the Training Advisory Group (TAG), who will give feedback to the Director and Major Foreign Collaborator on issues relating to the focus of training workshops in India and ideas for more collaborative grants between and across the institutions. Trainees in this program will have the opportunity to take formal courses, attend seminars and tutorials and work with their mentors apprenticeship- style. Training in the responsible conduct of research is a major emphasis of this program. Through our expanded program with three Indian sites, one with increased capacity, and two in critical need of infrastructure building, and our new networks of focus, we will develop sustainable partnerships to intervene with some of the most burdensome CNCDs in the world.
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Patterns and neurocognitive consequences of opioid-alcohol polysubstance use
  • 批准号:
    10659347
  • 项目类别:
  • 资助金额:
    $44.78万
  • 财政年份:
    2023
  • 负责人:
    Linda B. Cottler
  • 依托单位:
All of Us Consortium of CTSA Community Engagement Programs
  • 批准号:
    10799349
  • 项目类别:
  • 资助金额:
    $186.3万
  • 财政年份:
    2022
  • 负责人:
    Linda B. Cottler
  • 依托单位:
All of Us Consortium of CTSA Community Engagement Programs
  • 批准号:
    10307020
  • 项目类别:
  • 资助金额:
    $186.3万
  • 财政年份:
    2022
  • 负责人:
    Linda B. Cottler
  • 依托单位:
Integrating Wastewater-Based Epidemiology into the National Drug Early Warning System Coordinating Center to Track Community Health Trends
  • 批准号:
    10375878
  • 项目类别:
  • 资助金额:
    $15.25万
  • 财政年份:
    2021
  • 负责人:
    Linda B. Cottler
  • 依托单位:
海外基金