Training Program in Oncogenic Signals and Chromosome Biology

描述(申请人提供)：这是加州大学戴维斯分校肿瘤信号和染色体生物学博士后T32项目的第一次续签申请。这一培训计划利用了加州大学戴维斯分校指定的癌症中心分子肿瘤学项目的综合优势，以及参与培训的教职员工在致癌信号和染色体生物学方面的卓越专业知识和培训记录。该计划涉及30名培训员，其中包括3名国家科学院成员，他们也是分子肿瘤学计划的骨干。每个培训师都有一个积极的、由校外资助的研究项目。参与的教职员工代表不同的学科，但有一个共同的主题焦点。在加州大学戴维斯临床和翻译科学中心的进一步支持下，癌症中心强大的临床研究部分促进了该计划的翻译方面。在第一个资助期内，该培训计划吸引了12名才华横溢的博士后研究员来到加州大学戴维斯分校。值得注意的是，这些研究员中的五人已经从NIH、国防部和CBCRP获得了竞争非常激烈的个人研究员资格，以继续他们在癌症生物学方面的培训。培训计划开发了一系列创新和有效的课程活动，提供致癌信号和染色体生物学的正式培训，负责任的研究行为教育，以及个人指导。一系列丰富多样的研讨会、会议、讨论小组、讲习班和务虚会提供了展示研究进展和扩大培训经验的机会，超出了培训员的实验室。该培训方案为117名学员提供了服务，其中包括39名符合培训补助金资格的博士后研究员，他们积极参与了一些培训赠款活动，因此，该培训方案比支持受训者更有价值。一个有效的行政结构已经到位，在这次更新中得到了进一步完善。一名董事和一名联合董事在一个活跃的执行委员会的指导下管理该项目。执行委员会的每一位成员都积极维护一个特定的项目组合，以加强项目活动。为了进一步发展培训计划，我们成立了一个由四名成员组成的咨询委员会。这两名外部顾问是类似的癌症导向培训项目的主任，其中一名还在加州大学戴维斯分校癌症中心的外部顾问委员会任职，负责分子肿瘤学项目。这两名内部成员都是经验丰富的导师，其中包括医学院执行副院长，他是培训和指导方面的权威。该培训计划旨在为我们的学员在学术或研究机构、生物技术行业或政府实验室的独立研究职业生涯做好准备。

DESCRIPTION (provided by applicant): This is the first renewal application for the UC Davis postdoctoral T32 program in Oncogenic Signals and Chromosome Biology. This training program takes advantage of the integrated strength of the Molecular Oncology Program at the UC Davis NCI-designated Cancer Center and the exceptional expertise and training records of the participating faculty members in oncogenic signals and chromosome biology. The program involves 30 trainers, including three National Academy members, who also form the backbone of the Molecular Oncology Program. Every trainer maintains an active, extramurally funded research program. The participating faculty members represent diverse disciplines but share a common topical focus. A strong clinical research component at the Cancer Center facilitates the translational aspect of this program, with further support from the UC Davis Clinical and Translational Science Center. Over the first funding period, the training program attracted an outstanding cohort of 12 highly talented postdoctoral fellows to UC Davis. Remarkably, five of these fellows have already moved on to very competitive, individual fellowships from NIH, DOD, and CBCRP to continue their training in cancer biology. The training program has developed an innovative and effective array of curricular activities that provide formal training in oncogenic signals and chromosome biology, education in the responsible conduct of research, and individual mentoring. A rich and diverse array of seminars, conferences, discussion groups, workshops, and retreats provide opportunities to present research progress and broaden the training experience beyond the trainer's laboratory. The training program added significant value above supporting trainees, as it serviced a cohort of 117, including 39 training grant eligible, postdoctoral fellows, who actively participate in some training grant activities. An effective administrative structure is in place that is further refined in this renewal. A director and a co-director administer the program, with guidance by an active executive committee. Each member of the executive committee actively maintains a specific portfolio to enhance the program activities. To further develop the training program, we have created a four-member Advisory Board. The two external advisors are directors of comparable cancer-oriented training programs, and one also serves on the External Advisory Board of the UC Davis Cancer Center with responsibility for the Molecular Oncology Program. The two internal members are highly experienced mentors and include the Executive Associate Dean of the School of Medicine, who is an authority in training and mentoring. The training program aims to prepare our trainees for independent research careers in academic or research institutions, biotechnology industries, or government laboratories.