Kansas IDeA Network of Biomedical Research Excellence

描述（由申请人提供）：堪萨斯大学医学中心（KUMC）提交了一份继续支持堪萨斯IDEA生物医学研究卓越网络（K-INBRE）的申请。K-INBRE将KUMC（牵头机构）与堪萨斯的两个主要博士学位授予机构（堪萨斯-劳伦斯大学，KU-L;堪萨斯州立大学，KSU）作为研究生合作机构（GPIs），并与七个本科生合作机构（UPls）。UPl包括六个堪萨斯大学本科校园（恩波里亚州立大学，英尺海斯州立大学，Haskell Indian Nations Univ.汉堡州立大学，沃什伯恩大学，威奇托州立大学）和兰斯顿大学（兰斯顿，OK）。哈斯克尔印第安民族大学和兰斯顿大学增加了网络的多样性，因为前者致力于美洲土著人的教育和培训，后者主要招收黑人本科生。堪萨斯计划的长期目标是通过建立在当前K-INBRE的成功基础上，加强该州在细胞和发育生物学方面的研究能力。K-INBRE的结构和运作原则是在前几年建立的，重点是生物医学研究、网络和校园间通信的培训以及复杂的生物信息学方案的存在。这些目标仍然是相似的，因为KINBRE对堪萨斯州的生物医学研究产生了重大影响，但新的项目是量身定制的，以适应与转化研究相关的新兴领域。KINBRE开展的方案在实现其既定目标方面取得了显著的成功。K-INBRE下一阶段的具体目标是：（1）维护和改善堪萨斯州细胞和发育生物学的现有多学科研究网络，加强沟通渠道和研究基础设施，（2）通过提供先进的生物信息学技术和教育，增强堪萨斯的科学技术知识和整合，（3）通过指导，跨学科的研究机会，刺激堪萨斯州的基础和转化研究。在这些目标中，改进K-INBRE的新功能包括扩大对研究职业的资助，以及监督和指导过程的改进，在我们的生物信息学网络中推广综合系统生物学方法，并将转化研究的培训纳入K-INBRE目标，以便使科学发现顺利进入临床竞技场。

DESCRIPTION (provided by applicant): The University of Kansas Medical Center (KUMC) presents an application for continued support for the Kansas IDeA Network for Biomedical Research Excellence (K-INBRE). The K-INBRE links KUMC (Lead Institution) with the two major doctoral-degree-granting institutions in Kansas (University of Kansas-Lawrence, KU-L; Kansas State Univ., KSU) as Graduate Partner Institutions (GPIs), and with seven Undergraduate Partner Institutions (UPls). UPls include six Kansas undergraduate campuses (Emporia State Univ., Ft. Hays State Univ., Haskell Indian Nations Univ., Pittsburg State Univ., Washburn Univ., Wichita State Univ.) and Langston Univ. (Langston, OK). Haskell Indian Nations Univ. and Langston Univ. increase diversity in the network as the first is devoted to education and training of native Americans and the second enrolls primarily black undergraduates. The long-range objective of the Kansas program is to strengthen the state's research capacity in Cell and Developmental Biology by building on the successes of the current K-INBRE. The structure and operational principles of the K-INBRE, which focus on training for biomedical research, networking and intercampus communication and the presence of a sophisticated bioinformatics program, were established during the previous years. These goals remain similar as the KINBRE has had a significant impact on biomedical research in the State of Kansas, but novel programs are tailored to fit new emerging areas associated with translational research. Programs conducted by the KINBRE have had measurable success in reaching their stated goals. The Specific Aims proposed for the next phase of the K-INBRE are to (1) maintain and improve the current multi-disciplinary research network in Cell and Developmental Biology in the State of Kansas, strengthening both communication channels and research infrastructure, (2) enhance science and technology knowledge and integration in Kansas by offering sophisticated bioinformatics technology and education, (3) stimulate basic and translational research in the State of Kansas via mentored, interdisciplinary research opportunities. Within these Aims, new features that improve the K-INBRE include broadening funding for research careers together with improvements in oversight and the mentoring process, promoting an integrated systems biology approach within our bioinformatics network, and incorporating training for translational research into the K-INBRE goals so as to smooth the progress of scientific discoveries into the clinical arena.