Gulf South Minority-based NCI Community Oncology Research Program

说明3 全面审查标准和影响3 融资机会公告(FOA)特定标准10 组织和结构10 临床试验研究计划12 癌症护理服务研究项目13 运营/数据管理15 对人类受试者的保护17 包括妇女、少数群体和儿童17 资源共享计划17 预算和支助期17 特别强调小组名册 描述(申请人提供)：海湾南部少数民族为主的NCI社区肿瘤学研究计划(GS-MB-NCORP)汇集了路易斯安那州两个少数民族为主的CCOP(MBCCOP)和一个NCCCP站点的综合临床试验计划，得到了成熟和资助的癌症护理提供研究以及健康差距和基于社区的参与性研究计划的支持。由新奥尔良路易斯安那州立大学医学院(LSUHSC-NO-MBCCOP)及其NCCCP合作伙伴巴吞鲁日玛丽·伯德·珀金斯癌症中心-圣母湖医院(MBP-OLOL)建立的MBCCOP加入了路易斯安那州西北部什里夫波特路易斯安那州立大学医学院(LSUHSC-SH-MBCCOP)的MBCCOP，创建了GS-MB-NCORP。该联盟整合了成熟和经验丰富的临床医生和研究人员团队，旨在通过领先的学术和社区医院网络，将最先进的癌症临床试验扩大到我们所服务的患者。路易斯安那州是美国癌症患者存活率最低的州之一，尽管它在所有类型的癌症中的发病率并不是最高的。对于服务不足的患者和少数族裔患者尤其如此，这显然反映了重大的健康差距。对这种差异的可能解释从社会经济和获得卫生保健的机会，到对遗传和生物差异知之甚少。路易斯安那州立大学的MBCCOP和MBP-OLOL的NCCCP独立致力于增加少数族裔和服务不足社区获得临床试验的机会，建立外展和教育计划，并扩大癌症护理提供研究和健康差异研究。2012年秋天，我们同意将我们的优势和经验结合到GS-MB-NCORP中，目标是通过整合我们的临床试验计划并将癌症护理提供和健康差距研究人员纳入临床试验过程，对癌症相关的健康差距产生更显著的影响。GS-MB-NCORP的目标是增加少数族裔和服务不足的人群参与临床试验，确定参与的障碍，并将社区纳入研究研究。为此，我们提出了以下具体目标。1)推进获得癌症临床试验的综合系统，以促进和便利患者的参与和登记，特别是在路易斯安那州服务不足的少数群体中。2)促进癌症护理提供研究计划，以确保我们有能力参与研究基地提出的研究计划，并最终设计出改善患者护理的方案。3)通过社区参与扩大健康差距研究方案，增加少数群体和未得到充分服务的人群参与临床试验

DESCRIPTION 3 OVERALL REVIEW CRITERIA AND IMPACT 3 FUNDING OPPORTUNITY ANNOUNCEMENT (FOA) SPECIFIC CRITERIA 10 ORGANIZATION AND STRUCTURE 10 CLINICAL TRIALS RESEARCH PROGRAM 12 CANCER CARE DELIVERY RESEARCH PROGRAM 13 OPERATIONS/DATA MANAGEMENT 15 PROTECTIONS FOR HUMAN SUBJECTS 17 INCLUSION OF WOMEN, MINORITIES, AND CHILDREN 17 RESOURCE SHARING PLAN 17 BUDGET AND PERIOD OF SUPPORT 17 SPECIAL EMPHASIS PANEL ROSTER DESCRIPTION (provided by applicant): The Gulf South-Minority Based-NCI Community Oncology Research Program (GS-MB-NCORP) brings together an integrated clinical trials program from two Minority Based CCOPs (MBCCOP) and an NCCCP site in the state of Louisiana, supported by well-established and funded Cancer Care Delivery Research and programs in Health Disparities and Community-Based Participatory Research. The MBCCOP established by the LSU School of Medicine in New Orleans (LSUHSC-NO-MBCCOP) and its NCCCP partner, the Mary Bird Perkins Cancer Center - Our Lady of the Lake Hospital (MBP-OLOL) in Baton Rouge, have joined the MBCCOP at the LSU School of Medicine in Shreveport (LSUHSC-SH-MBCCOP) in northwest Louisiana to create the GS-MB-NCORP. This consortium integrates well-established and experienced teams of clinicians and researchers with the aim of expanding access to state-of-the-art cancer clinical trials to the patients we serve, through a network of leading academic and community hospitals. Louisiana has one of the poorest survival rates for cancer patients in the United States, despite not having the highest incidence for all types of the disease. This is particularly true for underserved and minority patients, clealy reflecting a major health disparity. Possible explanations for this disparity range from socio-economic and access to health care, to poorly understood genetic and biological differences. The LSU MBCCOPs and the NCCCP at MBP-OLOL have independently worked to increase access to clinical trials for minority and underserved communities, establish outreach and education programs, and expand Cancer Care Delivery Research and Health Disparity studies. In the fall of 2012, we agreed to combine our strengths and experience into the GS-MB-NCORP with the goal of having a more significant impact on cancer associated health disparities by integrating our clinical trials programs and incorporating Cancer Care Delivery and Health Disparity researchers into the clinical trials process. The GS-MB-NCORP's goals are to increase the participation of minorities and underserved populations in clinical trials, identify barriers t participation, and incorporate the community in the research studies. To achieve this, we propose the following Specific Aims. 1) Advance an integrated system of access to cancer clinical trials that promote and facilitate the participation and enrollment of patients, in particlar underserved and minority populations in Louisiana. 2) Promote Cancer Care Delivery Research Programs to ensure our ability to participate in research initiatives proposed by the Research Bases, and eventually design protocols that improve the care of our patients. 3) Expand Health Disparities Research programs through community engagement to increase the participation of minority and underserved populations in clinical trials