Long-Term Consequences of Lymphoma and its Treatment

该方案的目的是吸引多达300名有兴趣参加NIA研究的受试者，作为NIH先前癌症治疗的后续研究的一部分。以前在美国国立卫生研究院治疗过的非霍奇金淋巴瘤或霍奇金氏病的受试者有资格参加这项研究。 该方案的招募将通过与以前签署了NIH淋巴瘤研究治疗知情同意书的参与者的联系来进行。该方案的联系方式是通过NIA临床研究单位。完成电话同意，并获得后续信息。 可以通过电话交谈要求提供健康史摘要；并不是在所有情况下都需要进行实际体检。 如果患者愿意现场参与这项研究，他/她可能会被要求来到位于马里兰州巴尔的摩海港医院的NIA临床研究单位，参与后续评估。 现场执行的评估/测试： 获得知情同意。血液测试是评估过程的一部分，包括全血计数(CBC)、血清化学、肝肾功能、甲状腺功能和其他常规测试。电池中可能包括病毒学测试；如果进行艾滋病毒(AIDS)测试，将使用单独的同意。其中一些血液也可能用于研究测试，这些测试可能在其他医院的临床实验室中无法获得，而且尚未确定其临床意义。研究血液测试的结果将不会报告给患者，因为临床意义或意义尚不清楚。出血量不超过100cc(少于7汤匙)。尿检：尿检可能包括常规的尿检以测量肾功能。 病史和/或体检：可要求提供受试者详细的病历摘要，并在考察访问前提供书面病历。NIA的医生或护士与参与者一起审查他们的病史，并进行身体检查，其中包括标准的心理问卷。特别注意治疗的长期后遗症。首席调查员与参与者讨论调查结果(实验室和体检等)，并根据诊断和治疗提供有关健康问题和风险的信息。 收集和分析长期生存信息。还将收集和分析发病率信息。今年没有出版物。

The intent of this protocol is to accrue up to 300 subjects who are interested in participating in NIA research studies as part of follow-up for previous cancer treatment at NIH. Subjects previously treated for Non-Hodgkins's lymphoma or Hodgkin's disease at the NIH are eligible for this study. Recruitment for this protocol will be through contact with participants who have previously signed informed consent for treatment on NIH study for lymphoma. Contact for this protocol is through the NIA Clinical Research Unit. A telephone consent is completed and follow-up information is obtained. A health history summary may be requested by phone conversation; actual physical exam may not be required in all cases. If a patient is willing to participate on site for this study, he/she may be asked to come to the NIA Clinical Research Unit located at Harbor Hospital, Baltimore, Maryland to participate in a follow-up evaluation. Evaluation/tests that are performed on site: Informed consent is obtained. Blood tests are performed as part of the evaluation process, including complete blood counts (CBC), serum chemistries, liver and kidney function, thyroid function and other routine tests. Virology tests may be included in the battery; If an HIV (AIDS) tests is performed, a separate consent will be used. Some of the blood may also be used for research tests that may not be available in other hospital clinical labs and for which no clinical significance has been determined. The results of research blood tests will not be reported to the patient as the clinical significance or meaning is not known. The amount of blood drawn will not exceed 100cc (less than 7 tablespoons). Urine Tests: Urine tests may include a routine urinalysis to measure kidney function. Health History and/or Physical Examination: A detailed summary of the subjects medical record may be requested, with written release of medical records prior to the study visit. A physician or nurse practitioner of the NIA reviews the participants medical history with them and performs a physical examination, which includes standard psychological questionnaires. Particular attention to long-term sequelae of treatment is paid. The Principal Investigator discusses the findings (laboratory and physical exam, etc) with the participant and provides information regarding health issues and risks based on the diagnoses and treatments. Long term survival information is collected and analyzed. Morbidity information will also be collected and analyzed. There are no publications this year.