Healthy Children for a Healthy Future (HC4HF):A Collaborative Health Disp. Res.*

描述（由申请人提供）：在各种暴露、条件、疾病和治疗中，儿童的健康存在有据可查的、普遍的和不可接受的种族和民族差异。这种差距不仅直接给儿童本身、家庭和社区带来负担，而且对几代人产生长期影响。华盛顿-巴尔的摩地区的特点是显著的收入不平等、居住隔离和儿童健康的显著差异。这一更新申请建立了健康儿童健康未来组织：协作健康差异卓越研究中心（HC 4 HF），并建立在霍华德大学（HU），儿童国家医学中心（CNMC），和儿科在约翰霍普金斯（JH）的儿童健康差异的研究和培训下的DC-巴尔的摩儿童健康差异研究中心部门的长期合作承诺。我们的工作结合了儿童健康差距的概念模型和寿命的角度来看，并专门致力于制定干预措施，以克服儿童健康差距。HC 4 HF的总体目标是提供一个广泛合作的，多学科和多机构的“家”的高效和有效的研究，培训和社区参与，旨在改善少数民族儿童的健康和克服儿童健康的差距在华盛顿-巴尔的摩地区。为了实现这一总体目标，我们致力于以下具体目标：1）实施严格的干预研究计划，以优化青春期关键发育期的健康，将早期暴露与长期成人和代际健康联系起来。这项工作将借鉴“移动的健康”方面的新兴技术（移动健康），如短信，以测试干预措施，针对两个高度相关的条件不成比例地影响城市非洲裔美国青少年（2型糖尿病风险/肥胖和暴力暴露）;（二）培训和指导初级教师所需的临床和转化研究技能，以进行与少数民族健康和健康相关的严格研究差距; 3）通过提供一个基于审查和评估地理定位健康指标的创新对话方案，并通过将社区咨询过程纳入培训，加强华盛顿-巴尔的摩地区的双向社区参与和外联; 4）：领导一个基础广泛，多学科，多机构，与合作联盟合作，协调和加强与华盛顿-巴尔的摩地区和全国少数民族儿童健康和健康差距有关的研究和培训。

DESCRIPTION (provided by applicant): There are well-documented, pervasive, and unacceptable racial and ethnic disparities in the health of children across a variety of exposures,conditions, diseases, and treatments. Such disparities not only directly burden children themselves, their families, and their communities, but also have long-term effects across multiple generations. The Washington, DC-Baltimore region is characterized by significant income inequality, residential segregation, and marked disparities in child health. This renewal application establishes the Healthy Children for a Healthy Future: a Collaborative Health Disparities Research Center of Excellence (HC4HF) and builds on the long-standing collaborative commitment of Howard University (HU), Children's National Medical Center (CNMC), and the Department of Pediatrics at Johns Hopkins (JH) to child health disparities research and training under the DC-Baltimore Research Center on Child Health Disparities. Our work incorporates a conceptual model of child health disparities and a lifespan perspective and Is specifically committed to the development of interventions to overcome child health disparities. The overall goal of HC4HF is to provide a broadly collaborative, multi-disciplinary and multi-institutional "home" for efficient and effective research, training, and community engagement designed to improve minority child health and overcome child health disparities in the Washington DC-Baltimore region. To achieve this overall goal, we address the following Specific Aims: 1): To implement a program of rigorous intervention research to optimize health during the critical developmental period of adolescence, which links early exposures to long-term adult and intergenerational health. This work will draw on emerging technologies in "mobile health" (m-health), such as text messaging, to test interventions targeting two highly relevant conditions disproportionately affecting urban African American adolescents (Type 2 diabetes risk/obesity and violence exposure); 2) To train and mentor junior faculty in the required clinical and translational research skills required to conduct rigorous research relevant to minority health and health disparities; 3) To strengthen bidirectional community engagement and outreach in the Washington, DC-Baltimore region by providing an innovative program of dialogue based on review and evaluation of geo-located health indicators; and by integrating the community advisory process into training; 4): To lead a broadly based, multi-disciplinary, multi- institutional, and collaborative consortium to coordinate and strengthen research and training relevant to child minority health and health disparities in the Washington, DC-Baltimore region and nationally.