Behavior

核心B：行为核心--Jed Shumsky博士和Kassi Miller女士，联席董事 所有项目都提出康复治疗有利于再生、修复和康复 功能。行为通常被认为是中枢神经系统的最终共同输出。这需要复杂的协调 解剖底物、完整解剖底物的分子和电生理信号 解释看似简单的行为，如迈出一步或区分轻碰或有害接触 捏一下。因此，康复和行为测试技术的灵敏度、效度和可靠性是 不仅对个别项目的成功至关重要，而且对 计划项目作为一个整体。行为核心的目标是为PIS提供一个中央设施 提供康复训练和/或评估康复或细胞移植的功能意义 PIS提出的干预措施。行为核心为实验设计提供帮助， 配备至少7个康复训练标准范例和更多标准范例的中央设施 超过25种标准化的行为测试工具，用于测试运动、感觉运动、感觉和自主神经 脊髓损伤后对啮齿动物和猫的功能。最后，行为核心提供了个性化的手- 年为技术人员、研究生、博士后研究员、教员和访问教员提供技术培训 行为测试或康复策略。

CORE B: Behavior Core - Dr. Jed Shumsky and Ms. Kassi Miller, Co-Directors All projects are proposing that rehabiitative therapy is beneficial to regeneration, repair and recovery of function. Behavior is often noted as the final common output of the CNS. It requires the complex coordination of anatomical substrates, molecular and electrophysiological signals of intact anatomical substrates to elucidate seemingly simple behavior like taking a step or discriminating betiween a light touch or a noxious pinch. Therefore, the sensitivity, validity and reliability of rehabilitative and behavioral testing techniques are critical not only to the success of individual projects, but also for the success and interpretation of the Program Project as a whole. The goal of the Behavior Core is to provide a central facility to the Pis to provide rehabilitative training and/or assess the functional significance of rehabilitative or cellular grafting interventions proposed by the Pis. The Behavior Core provides assistance with experimental design, a centralized facility that is outfitted with at least 7 standardized paradigms for rehabilitative training and more than 25 standardized behavioral testing procotols to test motor, sensorimotor, sensory and autonomic function in rodents and cats after spinal cord injury. Finally, the Behavior Core provides individualized hands- on technical training for technical staff, graduate students, postdoctoral fellows, faculty and visiting faculty in behavioral testing or rehabilitative strategies.