Dartmouth Lead Participation in NCI National Clinical Trials Network

描述（由申请人提供）：诺里斯棉花癌症中心（NCCC），达特茅斯学院及其盖泽尔医学院和达特茅斯-希区柯克健康癌症相关活动的基石，将作为主要学术参与网站参加NCI的国家临床试验网络。NCCC在国家合作组临床试验方面有着悠久的领导历史，可以追溯到作为CALGB的运营中心，最近作为CALGB的继任者（联盟），RTOG和COG的正式成员，以及GOG的附属成员。作为北方新英格兰唯一一个由NCI指定的综合癌症中心，NCCC目前每年为5,200多名新的和30,000名返回的癌症患者提供服务。NCCC是佛蒙特州和新罕布什尔州的专业学术中心，锚定了一个由该地区17个以社区为基础的实践站点组成的网络，并接受罕见和晚期癌症的转诊，这是创新临床注册的目标人群。试验，从一个大的地理集水区。在达特茅斯，NCCC有一个中央临床研究办公室（OCR），负责协调全面参与整个可用的临床试验。NCCC打算参加所有6个有待NCI指定的网络，扩大其先前对参加联盟的关注。我们预计每年的收入接近 研究中成人受试者的400个入组学分，包括介入治疗试验中预计的74例知情同意受试者。卫生署的护理分为17个指定的跨学科 基于疾病的团队，每周召集14个相关专业，召开新患者会议，定期评估临床试验的招募资格。分配到这些临床肿瘤组（COG）的NCCC研究护士负责将可用的试验通知团队，NCCC临床试验管理系统（Velos eResearch）为团队提供跟踪当前入组的报告。虽然最优先考虑的是将NCCC科学转化为临床应用，但达特茅斯的规模排除了大多数单一机构研究，国家合作组试验优先于行业 为完成NCCC的临床研究使命而启动研究。

DESCRIPTION (provided by applicant): Norris Cotton Cancer Center (NCCC), the keystone of the cancer-related activities of both Dartmouth College, and its Geisel School of Medicine, and Dartmouth-Hitchcock Health, will participate in the NCI's National Clinical Trials Network as a Lead Academic Participating Site. NCCC has a long history of leadership in national cooperative group clinical trials, dating back to serving as an operating center for CALGB, and more recently as a full member of CALGB's successor (the Alliance), RTOG, and COG, and as an Affiliate member of GOG. As the only NCI-designated Comprehensive Cancer Center in northern New England, NCCC currently serves annually over 5,200 new and 30,000 returning cancer patients. NCCC is the specialty academic center for Vermont and New Hampshire, anchoring a network of 17 community- based practice sites across the region and receiving referrals of rare and advanced cancers, the target population for enrollment on innovative clinical. Trials, from a large geographic catchment area. Within Dartmouth, NCCC has a central Office of Clinical Research (OCR) which coordinates full participation in the entire range of available clinical trials. NCCC intends to participate in all 6 pending NCI-designated networks, expanding its prior focus on participation in the Alliance. We anticipate earning annually close to 400 enrollment credits for adult subjects on studies, including a projected 74 consented subjects on interventional therapeutic trial s. Care at DH is organized into 17 designated interdisciplinary disease-based teams which bring together all relevant specialties, 14 on a weekly basis, for new patient conferences at which eligibility for enrollment on clinical trials is assessed routinely. NCCC research nurses assigned to these Clinical Oncology Groups (COGs) are responsible for keeping the teams informed of available trials, and the NCCC clinical trials management system (Velos eResearch) provides the teams reports tracking current enrollment. While highest priority is given to translating NCCC science into clinical application, Dartmouth's size precludes most single-institution studies, and national cooperative group trials are prioritized ahead of industry initiated studies for fulfillment of NCCC's clinical research mission.