TRAINING IN LUNG SCIENCE

简介(申请人提供)：本计划是本会第四次更新肺科学训练资助金。在过去的18年半里，培训补助金为71名学员提供了在肺科学方面打下坚实基础的机会，其中包括42名医学博士、13名博士和16名博士前研究生。在完成T32支持的12名博士后学生中，有3人在教职，1人是CDC的研究员，7人仍在接受培训，1人是行业科学家，10名博士后学员不再获得T32支持，4人在教职，1人在Fogarty奖学金下进行研究，3人是学术或行业的研究科学家。在接受支持的18名医学博士后实习生中，有11人进入了学院教职，10人仍在教职。我们增加了医学博士实习生和这笔赠款所支持的代表性不足的少数群体的纳入。我们的培训计划的三个主要目标是：(1)为内科科学家提供3年严格的科学培训，使他们能够成为研究与人类肺部疾病相关的科学问题的独立调查人员；(2)为专注于肺部生物学研究并促进该领域长期职业生涯的博士科学家提供长达3年的博士后培训；以及(3)培训MD-PhD计划和其他已有学位授予计划的研究生--并指导他们进入肺部研究领域。MD实习生被强烈鼓励获得更高的学位，以优化他们成功的调查生涯的机会。该计划涵盖的三个主要课程领域是：(1)细胞和分子生物学；(2)系统生物学、生物工程和生物信息学；以及(3)临床和公共卫生研究。该课程为生物化学、分子生物学和生物化学博士学位、遗传学、细胞生物学与发展、微生物学、免疫学、癌症生物学、生物工程、生物信息学、公共卫生或临床研究硕士学位或临床研究证书课程提供正规培训和学位机会。培训教师来自4所学术卫生中心学院和理工学院。教师的专业知识范围广泛，包括：肺纤维化；肺损伤；肺癌；慢性阻塞性肺疾病；睡眠医学；哮喘；囊性纤维化；以及生物伦理学。每个领域的综合资源和稳定的研究资金提供了出色的培训环境。

DESCRIPTION (provided by applicant): This proposal is the fourth competing renewal of our Training Grant in Lung Science. During the last 18 and a half years, the Training Grant has provided 71 trainees the opportunity to develop strong foundations in lung science, including 42 MDs, 13 PhDs and 16 Predoctoral graduate students. Of the 12 predoctoral students who completed T32 support, three are in faculty positions, one is a staff scientist at CDC, seven are still in training and one is an industry scientist Among the 10 postdoctoral PhD trainees who no longer are T32-supported, four are in faculty positions, one is doing research with a Fogarty fellowship and three are research scientists in academics or industry. Eleven of the 18 MD postdoctoral trainees who received support entered academic faculty positions and ten remain as faculty. We have increased the inclusion of MD-PhD trainees and under-represented minorities supported by this grant. The three major aims of our Training Program are to: (1) provide 3 years of rigorous scientific training for physician-scientists, enabling them to become independent investigators examining scientific questions related to human lung disease; (2) provide up to 3 years of post-doctoral training to PhD scientists focusing their studies in lung biology and promoting long term careers in this field; and (3) train graduate students from the MD-PhD program and other established degree-granting programs - and guide them into careers in lung research. MD trainees are strongly encouraged to obtain advanced degrees to optimize their opportunities for a successful investigative career. The three major curricular areas encompassed by the program are: (1) Cell & Molecular Biology; (2) Systems Biology, Bioengineering; & Bio-Informatics; and (3) Clinical & Public Health Research. The curriculum provides formal training and degree opportunities for PhD degrees in Biochemistry, Molecular Biology & Biochemistry; Genetics, Cell Biology & Development; Microbiology, Immunology; & Cancer Biology; Bioengineering; Bioinformatics; for Masters degrees in Public Health or Clinical Research; or for Certificate Program in Clinical Research. The Training Faculty is drawn from 4 Academic Health Center colleges and the College of Science & Engineering. Faculty expertise extends across a broad spectrum, including: pulmonary fibrosis; lung injury; lung cancer; COPD; sleep medicine; asthma; cystic fibrosis; and bioethics. Comprehensive resources and stable research funding in each area provide an outstanding training environment.