Research Translation Core: Translating Research to Detect and Bioremediate

项目总结（见说明）： 研究翻译核心（RTC）将与我们的超级基金研究计划（SRP）中心的科学家和合作伙伴合作，以确定细胞生物测定，基于化学传感器的技术和基因工程植物可用于改善水，沉积物和土壤中超级基金毒物的检测和生物修复的方法。我们的伙伴关系建立在我们已经与部落、行业、联邦、州和地区政府机构以及全国SRP网络同事建立的密切工作关系的基础上。RTC将与29 Palms Tribal EPA，美国EPA和所有UCSD SRP实验室密切合作。总体目标有两个方面：第一，提高部落民族使用尖端生物分子和化学传感器技术检测和生物治理超级基金有毒物质的能力;第二，通过边干边学的过程，确定可供部落以及其他关心保护环境和人类健康的人商业使用的SRP科学和技术应用。RTC有四个具体目标：1）加强我们与位于加州Coachella的29 Palms Tribal EPA的长期合作伙伴关系，2）在真实的世界条件下对新的SRP技术进行现场测试和微调; 3）创建一个可访问的Web应用程序，用于科学研究。 超级基金毒物的绘图和空间分析;以及4）向广大受众有效传播新兴知识和技术，以加速社会学习和SRP研究成果的实际应用。为了实现这些目标，我们将确定和协调每个SRP项目的研究翻译机会，与NIEHS的SRP工作人员进行沟通，并与全国其他SRP中心进行合资企业（包括关于部落科学和大学部落科学伙伴关系价值的论坛）。 RTC将与圣地亚哥工业环境协会和其他合作伙伴合作，举办一系列论坛（新生物学前沿），鼓励公众讨论UCSD SRP和国家SRP网络产生的知识和技术。我们将系统地评估我们的进展，以满足这些目标使用逻辑模型与输入从我们中心的内部咨询委员会。我们将与行业、美国环保署、美国毒物与疾病登记署、PEPH和NIEHS研究翻译网络分享我们的进展和经验教训。

PROJECT SUMMARY (See instructions): The Research Translation Core (RTC) will work with our Superfund Research Program (SRP) Center scientists and partners to identify ways in which cellular bioassays, chemical sensor-based technologies, and genetically engineered plants can be used to improve the detection and bioremediation of Superfund toxicants in water, sediment and soil. Our partnership approach builds on close working relationships we already have in place with tribes; industry; federal, state and regional government agencies, and SRP network colleagues nationally. The RTC will work closely with the 29 Palms Tribal EPA, the U.S. EPA and all the UCSD SRP labs. The overarching objective is twofold: first, increase the capacity of Tribal Nations to use cutting-edge biomolecular and chemical sensor-based technologies for detecting and bioremediating Superfund toxicants; and second, identify SRP science and technology applications through a process of learn-by-doing that have potential for commercial use by tribes as well as others concerned about protecting environmental and human health. The RTC has four specific aims: 1) Strengthen our long-standing partnership with the 29 Palms Tribal EPA in Coachella, California, 2) Field test and fine-tune new SRP technologies under real world conditions; 3) Create a publically accessible web application for scientific mapping and spatial analysis of Superfund toxicants; and 4) Effectively disseminate emerging knowledge and technologies to broad audiences to accelerate social learning and practical applications of SRP research findings. To achieve these Aims we will identify and coordinate research translation opportunities with each SRP project, communicate with SRP staff at NIEHS, and do joint ventures with other SRP Centers nationwide (including a forum about tribal science and the value of university-tribal science partnerships). The RTC will work with the San Diego Industrial Environmental Association, and other partners, to host a series of Forums {Frontiers in New Biology) that encourage public discussion around the knowledge and technologies emanating from UCSD's SRP and from the national SRP network. We will systematically evaluate our progress toward meeting these aims using a logic model with input from our Center's internal advisory committee. We will share our progress and lessons learned with industry, the U.S.EPA, ATSDR, PEPH, and the NIEHS Research Translation network.