Child Health Career Development Program at UCSF

描述（由申请人提供）：根据RFA-HD-13-011，儿童健康研究职业发展奖（CHRCDA）计划，通过CHRCDA机制向年轻儿科研究者提供K12奖，提交了本修订提案。该申请要求每年有四名儿科医生获得医学博士或医学博士/博士学位，并在临床专科完成了奖学金培训。该计划的基本原理是基于对儿科医生的职业发展的支持，使他们成为完全独立和富有成效的基础科学研究人员，以及UCSF拥有培养下一代儿科科学领导者的愿景，经验和基础设施这一事实。我们的目标是(1)为培养学术儿科医生提供一个结构化的项目，(2)促进职业发展并促进初级教师的保留，(3)让有前途的早期职业儿科医生接触到加州大学旧金山分校研究的丰富知识，(4)促进学术儿科的多样性。该项目培养的学者将为儿童健康问题的诊断、治疗和预防以及儿童发病的成人疾病带来最先进的方法。该计划的设计涉及利用世界级基础实验室科学家的专业知识，他们将作为跨学科培训的导师。基础科学培训计划围绕七个科学核心：癌症、心肺医学、发育生物学、遗传学、免疫学、神经生物学和干细胞生物学。每个核心都有一个主任，指定的教员和一个特定的教学课程。这些学者，与他们的导师和核心主任一起，还将根据申请人之前的经验和培训以及受训者研究的科学主题，参加一个额外的学科特定课程的项目，这些课程可能在不同的核心之间重叠。我们相信，加州大学旧金山分校的儿科部门有远见，有经验，有基础设施来培养下一代学术儿科的领导者。在本申请中，我们提供了证据，证明该部门与更广泛的UCSF研究社区一起构成了一个特殊的环境，为准备年轻的儿科医生，他们将通过CHRCDA机制获得支持，成为成功的基础科学研究人员。例如，加州大学旧金山分校有1000多个研究实验室和2200多个活跃的研究项目，目前有4位诺贝尔奖获得者、41位美国国家科学院院士、61位美国艺术与科学院院士、72位医学研究所院士和16位霍华德休斯医学研究所研究员。这一方案是对未来儿童健康的一项投资，因为多样化

DESCRIPTION (provided by applicant): This revised proposal is submitted in response to RFA-HD-13-011, Child Health Research Career Development Award (CHRCDA) Program to provide K12 awards through the CHRCDA mechanism to young pediatric investigators. The application requests resources to support four pediatricians each year who hold MD or MD/PhD degrees and have completed scholarship training in a clinical subspecialty. The rationale for the program is based on the well-documented and urgent need to support mentored career development for pediatricians to enable them to become fully independent and productive basic science researchers, and the fact that UCSF has the vision, experience and infrastructure to train the next generation of leaders in pediatric science. Our aims are to (1) offer a structured program for training academic pediatricians, (2) foster career development and promote retention of junior faculty, (3) expose promising early career pediatricians to the intellectual richness of UCSF research and (4) promote diversity in academic pediatrics. The scholars trained by this program will bring state-of-the-art approaches to bear on diagnosis, treatment and prevention of health problems in children as well as childhood onset of adult illness. The design of this program involves harnessing the expertise of world-class basic laboratory scientists who will serve as mentors for interdisciplinary training. The basic science training program is focused around seven scientific cores: cancer, cardiopulmonary medicine, developmental biology, genetics, immunology, neurobiology, and stem cell biology. Each core has a Director, designated faculty, and a specific didactic curriculum. The scholars, in conjunction with their mentor and Core Director, will also participate in a program of additional discipline-specific course work dependent on both the prior experience and training of the applicant and the scientific theme of the trainee's research, which may often overlap amongst different cores. We believe that the Department of Pediatrics at UCSF has the vision, experience, and infrastructure to train the next generation of leaders in academic pediatrics. In this application, we provide evidence that the Department together with the broader UCSF research community comprise an exceptional environment for preparing young pediatricians who will receive support through the CHRCDA mechanism for successful careers as basic science researchers. For example, there are over 1,000 research laboratories and over 2,200 active research projects at UCSF, and the faculty currently includes 4 Nobel laureates, 41 National Academy of Sciences members, 61 American Academy of Arts and Sciences members, 72 Institute of Medicine members, and 16 Investigators of the Howard Hughes Medical Institute. This program is an investment in the future of children's health, as the diverse group of researchers we will train will harness advanced research strategies to address urgent problems (e.g., asthma, cancer, infectious diseases, host defense defects, diabetes, obesity, and developmental malformations of the heart, brain, and other organs), that will result in new treatments to improve child health outcomes.