NIDCD Core for Clinical Research and Care

NIDCD临床研究和护理核心支持以下NIDCD项目： 1 Z01-DC-000016核因子-kappaB在影响人类沟通的肿瘤分子发病机制和治疗中的作用 1 Z01 DC000031人体神经功能成像研究 1 Z01 DC000039综合征性和非综合征性耳聋基因的鉴定 1人类通讯障碍的Z01 DC000046遗传学研究 1 Z01 DC000057脑成像与建模 1 Z01 DC000060遗传性耳聋的分子生物学研究 1 Z01 DC000064听力平衡障碍的临床分析 头颈癌中1个Z01-DC-000073信号和转录因子网络的相互作用 头颈癌的1个Z01-DC-000074基因组和蛋白质组学研究 核心支持的NIDCD协议包括： T-DC-0005注意力测量方法的研究 Oh93-DC-0016-非综合征遗传性耳聋基因图谱：印度/巴基斯坦方案 92-DC-0178-言语运动控制和语言处理的功能神经成像研究 97-DC-0057-口吃的非参数和参数链接研究 97-DC-0180-遗传性耳聋的遗传分析 00-DC-0073-遗传性听觉处理缺陷的鉴定 01-DC-0099-NIDCD头颈外科分会临床研究方案评价 01-DC-0228-前庭导水管扩大所致听力损害的临床和分子分析 01-DC-0229-遗传性听力和平衡障碍的遗传分析 01-DC-0230-味觉缺陷研究 06-DC-0218-耳鸣的神经模型和脑成像 10-D-180-雷帕霉素治疗晚期头颈癌的先导性研究 NIDCD临床研究和护理核心每年支持3000多个门诊评估。耳鼻咽喉科核心医生每年要做50-100例大手术。在高级临床助理期间，工作人员指导医学生。耳鼻咽喉科医生科学家职业发展计划通过强迫症协调，在过去的一年里招募了两名候选人。 合作研究为书目中列出的几个已发表的手稿做出了贡献。

The NIDCD Core for Clinical Research and Care supports the following NIDCD projects: 1 Z01-DC-000016 NF-kappaB in the molecular pathogenesis and therapy of Neoplasms Affecting Human Communication 1 Z01 DC000031 Functional Neuroimaging Studies in Humans 1 Z01 DC000039 Identification of Genes Causing Syndromic And Nonsyndromic Hearing Impairment 1 Z01 DC000046 Genetic Studies of Human Communications Disorders 1 Z01 DC000057 Brain Imaging And Modeling 1 Z01 DC000060 Molecular Analysis Of Human Hereditary Deafness 1 Z01 DC000064 Clinical Analysis Of Disorders Of Hearing And Balance 1 Z01-DC-000073 Signal and Transcription Factor Network Interactions in Head and Neck Cancer 1 Z01-DC-000074 Genomics and Proteomics of Head and Neck Cancer The NIDCD protocols supported by the core include: T-DC-0005 Studies of Measures of Attention Oh93-DC-0016 - Nonsyndromic Hereditary Hearing Impairment Gene Mapping: India / Pakistan Protocol 92-DC-0178 - Functional Neuroimaging Studies of Speech Motor Control and Language Processing 97-DC-0057 - Non-parametric and parametric Linkage Studies of Stuttering 97-DC-0180 - Genetic Analysis of Human Hereditary Hearing Impairment 00-DC-0073- Identification of Hereditary Auditory Processing Defiicts 01-DC-0099 - Evaluation for NIDCD Head and Neck Surgery Branch Clinical Research Protocols 01-DC-0228 - Clinical and Molecular Analysis of Hearing Impairment Associated with Enlarged Vestibular Aqueducts (EVA) 01-DC-0229- Genetic Analysis of Hereditary Disorders of Hearing and Balance 01-DC-0230 - Studies in the Deficits in the Sense of Taste 06-DC-0218 - Neural Modeling and Brain Imaging of Tinnitus 10-D-180 - Pilot Study of neoadjuvant rapamycin for patients with advanced head and neck cancer The NIDCD Core for Clinical Research and Care supports over 3,000 outpatient clinic evaluations per year. Core otolaryngologists perform 50-100 major surgical cases annually. Staff mentor medical students during senior clinical clerkships. The Otolaryngolist Surgeon Scientist Career Development Program coordinated through the OCD, recruited two candidates in the past year. Collaborative studies resulted in contributions to several published manuscripts listed in the Bibliography.