FASEB SRC on Biology and Chemistry of Vision

 描述（由申请人提供）：本申请寻求资金的部分支持连续三个两年一度的美国实验生物学学会联合会（FASEB）科学研究会议上的“生物学和化学的视觉”。自1985年成立以来，这一直是光感受器生物学最成功和最有影响力的会议之一。会议的主要目标是汇集成熟和年轻的科学家，讨论光感受器生物学和病理生物学广泛而多样的领域的最新进展。相对较少的与会者人数（通常低于150名与会者）旨在通过将新颖实验结果的高质量正式演示与友好的合议氛围中的非正式互动相结合来促进科学交流。会议还对该领域的年轻调查人员具有巨大的教育和网络价值。因此，本申请所要求的资金将用于 支付青年科学家的旅费和会议费，包括博士前和博士后学员以及尚未获得NIH资助以支持其研究项目的初级研究人员。每次会议的计划将提供该领域最新研究的关键概述，及时解决问题和新兴趋势，并作为合作和未来工作的催化剂。沿着这些路线，2015年会议将有九个平台和两个海报会议，涵盖感光体生物学和化学的广泛领域。第一次会议将讨论视网膜蛋白的结构，功能和遗传学。 第二个将通过覆盖光感受器和视网膜色素上皮之间的功能相互作用打开光感受器细胞生物学的主题。第三部分将考虑感光突触机制。第四部分是会议的一个鼓舞人心的亮点，将为该领域最重要的突破提供历史背景，涵盖当前趋势，并考虑该领域未来的方案目标。第五部分将在睫状细胞生物学的更广泛的背景下突出光感受器功能和变性。第六届会议将讨论从基因治疗到干细胞等一系列现代视觉功能恢复方法。第七章将讨论光感受器病理学的最新进展。第八部分将涵盖光感受器调节的新机制，特别关注非编码RNA的作用。最后一个简短的会议将保留给目前最令人兴奋的最新消息，从外地。我们的计划旨在最大限度地提高来自代表性不足群体的学员，年轻调查人员和科学家的参与度。除了传统形式的定期和简短的演讲外，十六名学员将在两个海报会议之前举行的广受欢迎的"数据闪电战"会议上介绍他们的海报演示的五分钟亮点。

 DESCRIPTION (provided by applicant): This application seeks funds for partial support of the three consecutive biennial Federation of American Societies of Experimental Biology (FASEB) Science Research Conferences on the "The Biology and Chemistry of Vision". Since its inception in 1985, this has been one of the most successful and influential meetings focused on photoreceptor biology. The major goal of the meeting is to bring together established and young scientists to discuss the most recent advances in the broad and diverse fields of photoreceptor biology and pathobiology. The relatively small number of attendees (typically under 150 participants) is designed to catalyze scientific interchange by combining high- quality, formal presentations of novel experimental results with informal interactions in a friendly, collegial atmosphere. The meeting also has tremendous educational and networking value for younger investigators in the field. Accordingly, the funding requested in this application will be used for covering the travel expenses and conference fees for the young scientists, including pre- and post-doctoral trainees and junior investigators who have not yet received NIH funding to support their research programs. The program of each conference will provide a critical overview of the most recent research in the field, address timely questions and emerging trends, and serve as a catalyst for collaborations and future work. Along these lines, the 2015 conference will have nine platform and two poster sessions covering the broad fields of photoreceptor biology and chemistry. The first session will address the structure, function and genetics of retinal proteins. The second will open the theme of photoreceptor cell biology by covering the functional interactions between photoreceptors and the retinal pigment epithelium. The third will consider photoreceptor synaptic mechanisms. The fourth, intended as an inspirational highlight of the meeting, will provide historical context for the most critical breakthroughs in the field, cover current trends and consider future programmatic goals for the field. The fifth will highlight photoreceptor function and degeneration in the broader context of ciliary cell biology. The sixth will address the whole array of modern approaches to visual function restoration, from gene therapy to stem cells. The seventh will discuss the current advances in photoreceptor pathobiology. The eighth will cover new mechanisms of photoreceptor regulation, with a particular focus on the role of non-coding RNAs. And the last short session will be reserved to present the most exciting late-breaking news from the field. Our program is designed to maximize participation of trainees, young investigators and scientists from underrepresented groups. In addition to traditional formats of regular and short talks, sixteen trainees will presen five-minute highlights of their poster presentations at the popular "Data Blitz" sessions, held prior to each of the two poster sessions.