Brain Health Patient Safety Learning Laboratory

 描述(由申请人提供)：我们建议在印第安纳大学医学院与印第安纳大学信息学和计算机学院、印第安纳大学护理学院、普渡大学生物医学和工业工程学院、普渡大学药学院、雷根斯特里夫研究所，Inc.以及一个安全网医疗保健系统Eskenazi Health合作，建立脑健康患者安全学习实验室(“脑安全实验室”)。大脑安全实验室将允许这个新的专业网络集思广益，讨论大脑安全的解决方案，并在为弱势老年人服务的现实世界临床环境中快速部署和测试新想法。弱势老年人，包括低收入和少数族裔老年人，以及患有多发性疾病的老年人，是aq优先考虑的人群。 这项建议的具体目的是建立一个患者安全学习实验室，重点是在AHRQ优先考虑的高危人群中预防对大脑健康的伤害，以避免可避免的伤害。 大脑健康是成功衰老的首要任务之一。大脑健康包括认知和情绪健康以及积极的幸福感。在大脑健康的背景下，我们首先将重点放在与老年人使用药物有关的患者安全危害上。使用可能损害大脑健康的药物被广泛接受为患者安全问题，一直抵制早期干预努力。该医学研究所最近发布了一份关于认知老化的报告，其中包括呼吁政策制定者、医疗保健专业人员、患者和家庭采取联合和合作行动，以“审查患者的药物，关注已知对认知有影响的药物。”我们关注老年人，因为他们是药物使用、过度使用和滥用的最大蓄水池，特别容易受到大脑安全问题的影响。

 DESCRIPTION (provided by applicant): We are proposing to establish the Brain Health Patient Safety Learning Laboratory ("Brain Safety Lab") at the Indiana University School of Medicine in collaboration with the Indiana University School of Informatics and Computing, The Indiana University School of Nursing, The Purdue University Schools of Biomedical and Industrial Engineering, the Purdue College of Pharmacy, the Regenstrief Institute, Inc., and a safety net health care system, Eskenazi Health. The Brain Safety Lab will allow this new professional network to brainstorm about solutions to brain safety and to rapidly deploy and test novel ideas in real-world clinical settings serving vulnerable elders. Vulnerable elders, includin low-income and minority elders and those who suffer from multimorbility, are AHQ priority populations The specific aim of this proposal is to establish a patient safety learning laboratory focused on preventing harms to brain health among an AHRQ priority population at high risk for avoidable harm. Brain health is one of the highest priorities for successful aging. Brain health includes both cognitive and emotional health as well as positive sense of well-being. Within the context of brain health, we will focus initially on patient safety harms related to the use of medications among older adults. Use of medications that have the potential to harm brain health is widely accepted as a patient safety problem that has been resistant to early intervention efforts. The institute of Medicine recently issued a report on cognitive aging that included a call for joint an collaborative actions among policy-makers, health care professionals, patients, and families to "review patient medications, paying attention to medications known to have an impact on cognition." We focus on older adults because they are the largest reservoir of medication use, over-use, and misuse and are particularly vulnerable to brain safety concerns.