South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE)

 描述(申请人提供)：南卡罗来纳州IDEA卓越生物医学研究网络(SC INBRE)是由三所综合研究大学(CRU)和七所以本科生为主的机构(PUI)组成的网络，在过去的资助期间，这两所大学一直在共同努力，追求共同的目标：在南卡罗来纳州建设生物医学研究基础设施，加强本科生研究培训，并促进所有学生，特别是代表不足的少数族裔和经济困难群体，获得医疗研究职业。SCINBRE目前的主题领域是生物工程/再生医学(主要在CRU)和细胞和分子生物学(主要在PPI)。此外，神经科学已经成为下一阶段发展的另一个优势领域。我们还看到生物信息学在研究主题领域和学生培训方面的利用有了很大的增长，这要归功于 生物信息学核心的努力。SC INBRE在本资助期取得了巨大的成功。在2009年以来接受研究培训的387名学生中，有172名是男性，215名是女性，超过33%的学生是代表性不足的少数民族。在196名进入研究生生涯的学生中，46%的人进入了研究生院，22%的人进入了医学/专业学校，27%的人在行业工作。在当前的资助期间，南加州大学INBRE的教职员工和学生制作了170多份出版物和300多份演示文稿，并从包括NIH和NSF在内的各种资金来源获得了总计超过3600万美元的额外赠款支持。SC INBRE为准备大型机构(HHMI)和中心拨款(COBRE)申请铺平了道路并提供了支持，这些申请(加在一起)为该州带来了超过1300万美元的研究资金。作为SC INBRE长期成员的PUI是该网络中新机构的榜样。在新的资助期内，我们建议通过将新的PUI纳入网络，并通过进一步增加跨机构的网络活动和联系，将SC INBRE的支持范围扩大到全州的教职员工和学生。为此，我们将实施发展研究项目(DRP)PR，并为DRP目标教师提供强有力的指导和培训以及职业发展机会；我们将通过院校SC INBRE本科生研究计划扩大每个网络PUI的学生的研究培训；我们将通过扩大试点项目计划来增加生物信息学核心的活动。改造三所科研设施。在选定地点与高中教师和学生进行接触将有助于提高学生的健康水平，加强SC INBRE在研究职业方面的渠道，积极鼓励和支持未被充分代表的少数族裔学生和来自未得到充分服务地区的学生继续接受大学教育并从事生物医学研究。

 DESCRIPTION (provided by applicant): The South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE) is a network of three Comprehensive Research Universities (CRU) and seven Predominantly Undergraduate Institutions (PUI) that have been working together during the past funding periods in pursuit of their common goals: to build biomedical research infrastructure and strengthen undergraduate research training in South Carolina, and to promote access to health research careers for all students, particularly underrepresented minorities and economically disadvantaged groups. The thematic areas of SC INBRE are currently Bioengineering/ Regenerative Medicine (primarily at the CRUs) and Cell and Molecular Biology (mostly at the PUI). In addition, Neuroscience has emerged as an additional area of strength upon which to build in the next phase. We have also seen much growth in the utilization of Bioinformatics within the research thematic areas and in student training, thanks to the efforts of the Bioinformatics Core. SC INBRE enjoyed tremendous success during the current funding period. Of the 387 students that received research training sine 2009, 172 were Males, 215 Females, and over 33% were Underrepresented Minorities. Of the 196 students who are well into their post-graduate careers, 46% went to graduate school, 22% to medical/professional school, and 27% hold industry jobs. In the current funding period, SC INBRE faculty and students produced over 170 publications and over 300 presentations, and generated additional grant support for a total of over $36 Million from a variety of funding sources including the NIH and the NSF. SC INBRE paved the way for and supported the preparation of applications for large institutional (HHMI) and Center grants (COBRE) that (all together) brought over $13 Million in research funds to the state. PUIs that have been long-time members of SC INBRE serve as role models to new institutions in the network. In the new funding period we propose to extend the reach ofSC INBRE's support to faculty and students across the state by including new PUIs in the network, and by further increasing network activities and connec across institutions. To this end, we will implement the Developmental Research Project (DRP) Pr complemented by strong mentoring and training and career development opportunities for the DRP target faculty; we will expand research training of students at each network PUI through the Institutional SC INBRE Undergraduate Research Programs; and we will increment the activities of the Bioinformatics Core with an expanded Pilot Projects program. We will renovate research facilities at three PUIs. Outreach to high school teachers and students at selected sites will help tions ogram, strengthen SC INBRE's pipeline to research careers that actively encourages and supports underrepresented minority students and students from underserved areas to pursue a college education and engage in biomedical research.