Core Grant for Vision Research

描述(由申请者提供)：索尔克生物研究所请求支持视力研究核心助学金的续期。索尔克视觉神经生物学中心(CNV)包括17个研究实验室，其中14个在索尔克研究所，以及加州大学圣地亚哥分校(UCSD)和斯克里普斯研究所(TSRI)的基础视觉研究小组。其中12个实验室目前由国家眼科研究所颁发的13个有效的R01奖助金资助，其中10个在索尔克研究所举行。这些视觉科学研究人员来自几个不同的部门，包括视觉中心、计算神经生物学、分子神经生物学、调节生物学和系统神经生物学实验室，以及索尔克研究所的认知神经科学实验室；TSRI的分子和细胞神经科学；以及加州大学圣地亚哥分校的心理学和神经生物学。CNV内的视觉研究涵盖了广泛的兴趣领域，包括视觉系统的发育和可塑性，了解视觉刺激的神经处理机制，视觉感知及其与行为的联系，以及病理学。除了管理核心，NEI P30核心赠款将继续支持对CNV研究工作至关重要的四个已建立的资源和服务核心：1)分子生物学和病毒学核心，2)非人类灵长类设施核心，3)机器车间核心，以及4)高级计算核心。每个核心将由至少七个核心调查人员大量使用，机器车间和高级计算核心支持中心的所有成员。NEI对CNV视觉研究核心助学金的支持将继续促进新的跨学科合作，支持和加强这些研究努力之间存在的重大协同效应，并为新项目和研究计划的开发提供基础。核心支持还将为索尔克研究所提供重要的杠杆作用，以刺激外部慈善事业，并招募受训人员和其他新的调查人员，进一步扩大研究所的视力研究，推进国家眼科研究所的使命。

DESCRIPTION (provided by applicant): The Salk Institute for Biological Studies requests support for renewal of the Core Grant for Vision Research. The Salk Center for the Neurobiology of Vision (CNV) includes 17 research laboratories, 14 at The Salk Institute and basic vision research groups at the University of California at San Diego (UCSD) and The Scripps Research Institute (TSRI). Twelve of these laboratories are currently funded through 13 active R01 grant awards from the National Eye Institute, 10 of them held at The Salk Institute. These vision science investigators come from several different departments, including the Vision Center, Computational Neurobiology, Molecular Neurobiology, Regulatory Biology and Systems Neurobiology Laboratories, and the Laboratory for Cognitive Neuroscience at The Salk Institute; Molecular and Cellular Neuroscience at TSRI; and Psychology and Neurobiology at UCSD. Vision research within the CNV covers broad areas of interest, including visual system development and plasticity, understanding the mechanisms of the neural processing of visual stimuli, visual perception and their link to behaviors, and pathology. In addition to the Administrative Core, the NEI P30 Core Grant will continue support of four established resource and service cores that are critical for CNV research efforts: 1) Molecular Biology and Virology Core, 2) Non-Human Primate Facility Core, 3) Machine Shop Core, and 4) Advanced Computing Core. Each of the cores will have significant use by at least seven core investigators, with the Machine Shop and Advanced Computing Cores supporting all members of the Center. NEI support for the CNV Core Grant for Vision Research will continue to foster new interdisciplinary collaborations, supporting and enhancing the significant synergies that exist between these research efforts and providing the basis for the development of new projects and research programs. Core support will also provide significant leverage for The Salk Institute to stimulate outside philanthropy and to recruit trainees and other new investigators, further expanding vision research at the Institute and advancing the mission of the National Eye Institute.