Targeted Research and Academic Training of Nurses in Genomics

 描述（由申请人提供）：这个机构NRSA的竞争性续期申请的目标是继续为遗传和基因组研究领域的博士前和博士后水平的护士提供教育和培训。基因组研究继续相关的护理研究，证明了基因组护理科学的蓝图，最近出版的发展。使研究工作承担临床相关问题需要一个连续的干部的个人接受国家的科学教育和培训，使他们能够将基因组学纳入他们的研究轨迹。护士在弥合基因组学研究和临床实践之间的差距方面具有独特的地位。他们在生命的各个阶段和所有临床领域与患者互动。他们的工作本质上是跨学科的。由于基因组学被纳入全国各地的护理课程，更多的护士正在接受基因组学教育。然而，在进行尖端基因组学研究方面，长期在实验室接受培训的机会仍然很少。这样的培训机会是必不可少的，因为几乎每一个条件研究的护士科学家，包括那些对教师的匹兹堡大学，护理学院，有一个遗传成分。我们的目标是培养有才华的护士科学家，在他们的职业生涯的开始阶段，制定相关的应用和评估基因组学在改善患者的结果研究轨迹。培训计划的目标是准备博士前和博士后学员将基因组学纳入他们的研究轨迹使用教学课程，临床轮换，期刊俱乐部，研讨会，个性化的实践，实验室经验，并在科学会议上演示。该计划的目标侧重于以下方面的培训：1）将基因组学纳入理论/概念框架; 2）基因组学研究方法（例如，家族研究、全基因组关联研究、基因表达研究）; 3）基因组学实验室技术; 4）基因组学的临床应用; 5）生物信息学和基因组大数据的适用性。为什么匹兹堡大学护理学院仍然是这样一个培训计划的理想环境的原因在应用程序中进行了阐述。

 DESCRIPTION (provided by applicant): This competing renewal application for an Institutional NRSA has the goal of continuing to providing education and training to nurses at the predoctoral and postdoctoral level in the field of genetic and genomic research. Genomic research continues to relevant for nursing research, evidenced by the development of A Blueprint for Genomic Nursing Science that was recently published. Bringing research efforts to bear upon clinically relevant issues requires that a continuous cadre of individuals receive state of the science education and training to allow them to incorporate genomics into their research trajectories. Nurses are uniquely positioned to bridge the gap between genomics research and clinical practice. They interact with patients at all stages of life, and in all clinical arenas. Teir work is interdisciplinary by nature. More nurses are now receiving education in genomics because of the inclusion of genomics into nursing curricula across the country. Nevertheless, there continue to be few opportunities for long-term laboratory-based training in the conduct of cutting-edge genomics research. Such training opportunities are essential because nearly every condition studied by nurse scientists, including those on the faculty of the University of Pittsburgh, School of Nursing, has a genetic component. Our objective is to train talented nurse scientists, at the beginning stages of their careers, to develop research trajectories related to the application and evaluation of genomics in improving patient outcomes. The goal of the training program is to prepare predoctoral and postdoctoral trainees to incorporate genomics into their research trajectories using didactic courses, clinical rotations, journal clubs, seminar, individualized practica, laboratory experiences, and presentations at scientific meetings. Objectives of the program focus on training in: 1) the integration of genomics into theoretical / conceptual frameworks; 2) genomics research methodology (e.g., family studies, genome-wide association studies, gene expression studies); 3) genomics laboratory techniques; and 4) clinical application of genomics; and 5) applicability of bioinformatics and genomic Big Data. Reasons why the School of Nursing at the University of Pittsburgh continues to be the ideal environment for such a training program are elaborated in the application.