Animal Care Core

精确的表型分型在很大程度上取决于动物受试者的质量。稳定的住房和畜牧业 最大限度地减少可能扭曲表型结果的外源因素的影响。此外，小鼠 提交给麻省大学MMPC共享空间与来自微生物多样性来源的队列。他们作为 以及居住在定居点中的小鼠，必须保护其免受外来感染的潜在交叉感染。 剂.动物护理中心在Jerald Silverman博士作为核心主任的监督下运作， 他负责监督马萨诸塞大学医学院的动物护理设施。动物护理中心提供设施 和与这些优先事项有关的服务，具体目标如下：（1）提供稳定的， 为小鼠（2）提供专门的圈养室， （LRB的Podl-124）和现场表型分析程序，（3）评估每种微生物的微生物学特征 队列，并为中心主任提供有关结果的解释和建议，以及（4） 根据中心主任的决定，向表型分析服务的用户提供结果和建议 对提交的小鼠的健康状况进行评估。动物护理核心的目标是支持 麻省大学MMPC与动物护理和表型小鼠质量有关的问题。

Precise phenotyping depends significantly on the quality of animal subjects. Stable housing and husbandry minimize the influence of exogenous factors that could distort phenotyping results. Additionally, mice submitted to the UMass MMPC share space with cohorts from microbiologically diverse sources. They, as well as mice housed in resident colonies, must be protected against potential cross-infection by adventitious agents. The Animal Care Core operates under the supervision of Dr. Jerald Silverman as the Core Director, who oversees the animal care facility of UMass Medical School. The Animal Care Core provides facilities and services relevant to these priorities under the following specific aims: (1) to provide stable, biocontainment housing, husbandry and health care for mice (2) to provide a dedicated room for housing (Podl-124 of LRB) and on-site phenotyping procedures, (3) to assess the microbiological profile of each cohort and provides the Center Director with interpretation and advice regarding the results, and (4) to provide to the users ofthe phenotyping service, at the discretion ofthe Center Director, results and advice on the health status of submitted mice. The goal of the Animal Care Core is to support the operation of UMass MMPC with issues pertinent to animal care and quality of phenotyping mice.