CAI2R Technology Research and Development Project #1: Towards Rapid Continuous Comprehensive MR Imaging: New Methods, New Paradigms, and New Applications

项目总结：技术研究与开发项目1 迈向快速、连续、全面的磁共振成像：新方法、新范式和新应用 R&D#1主要调查人员： 里卡多·奥塔佐博士和丹尼尔·K·索迪克森博士 我们高级成像创新与研究中心(CAI2R)的广泛使命是将 合作的翻译研究团队，用于开发高影响的生物医学成像技术， 最终目标是改变日常的临床实践。技术研究与开发(R&D) 项目1的目标是在成像方面新使用时间，采用前沿的快速图像采集和 高级图像重建，可通过以下方式取代传统的复杂、有针对性且低效的成像协议 简单、全面、批量的收购，包含有关多个互补产品的丰富信息 对比和不同的动态。具体目标如下： (1)新方法：开发新的快速磁共振获取和重建策略，专门针对 协作和服务项目的需求，利用压缩传感、并行成像和 基于模型的重建。 (2)新范式：建立新的MR扫描范式，使用不断更新的运动健壮性 全面收购，消除停滞时间，并通过用户- 定义了对比度和时空轮廓。 (3)新应用：在协作和服务项目中实施这种新的扫描模式，并进行评估 它在大容量、高影响临床应用的常规患者群体中的有效性。

Project Summary: Technology Research and Development Project #1 Towards Rapid Continuous Comprehensive MR Imaging: New Methods, New Paradigms, and New Applications TR&D #1 Principal Investigators: Ricardo Otazo, PhD and Daniel K. Sodickson, MD, PhD The broad mission of our Center for Advanced Imaging Innovation and Research (CAI2R) is to bring together collaborative translational research teams for the development of high-impact biomedical imaging technologies, with the ultimate goal of changing day-to-day clinical practice. Technology Research and Development (TR&D) project #1 aims at a new use of time in imaging, deploying leading-edge methods of rapid image acquisition and advanced image reconstruction to replace traditional complex, targeted, and inefficient imaging protocols with simple, comprehensive, volumetric acquisitions that contain rich information about multiple complementary contrasts and diverse dynamics. Specific aims are as follows: (1) New methods: Develop novel rapid MR acquisition and reconstruction strategies specifically tailored to the needs of collaborative and service projects, taking advantage of compressed sensing, parallel imaging and model-based reconstruction. (2) New paradigm: Establish a new paradigm for MR scanning, using continuously-updated motion-robust comprehensive acquisitions eliminating dead time, coupled with tailored image reconstructions with user- defined contrast and spatiotemporal profiles. (3) New applications: Implement this new scanning paradigm in collaborative and service projects and evaluate its efficacy in routine patient populations for high-volume high-impact clinical applications.