Clinical Research Design, Epidemiology, and Biostatistics Core

临床研究设计、流行病学和生物统计学(CRDEB)KCA将在实现CTR-IN目标方面发挥关键作用，CTR-IN目标是通过创建一个协调的基础设施，鼓励创新的临床和转化性研究，并加强我们对新老研究人员的培训。MWRC的大多数合作机构认识到，从最初的研究设计到数据分析和结果的有效交流，临床研究设计、流行病学和生物统计学对研究至关重要。因此，在这些领域的一些独立努力存在于整个水利部，并在某种程度上自主地运作。然而，对于一些研究人员来说，获取信息存在多重障碍。虽然许多成功和成熟的研究人员可以接触到这些小组，但其他研究人员的访问可能是有限的和随意的，特别是对较初级的研究人员。此外，没有为调查人员提供这种支持的协调系统。此外，西部山区支离破碎的自然和地理障碍也损害了临床研究设计、流行病学和生物统计学支持、合作和培训的有效整合和传播。为了克服这些障碍，CTR-IN将为在开发研究设计、生物统计学方法和流行病学设计方面需要帮助的临床和翻译研究人员提供本地和中央联络点。这将为临床和转化性研究营造一个充满活力和富有成效的氛围，并促进所有研究人员的研究，包括新的和初级的研究人员。

The Clinical Research Design, Epidemiology, and Biostatistics (CRDEB) KCA will play a crucial role in achieving the CTR-IN goal of accelerating the translation of scientific discovery into improved health by creating a coordinated infrastructure encouraging innovative clinical and translational research and enhancing our training of new and established researchers. The majority of MWRC partner institutions recognize that clinical research design, epidemiology, and biostatistics are critical to investigation, from initial study design through data analysis and the effective communication of results. As a result, a number of independent efforts in these areas exist throughout the MWRC and operate somewhat autonomously. However, multiple barriers to access exist for some researchers. While many successful and established researchers have access to these groups, other investigator's access may be limited and haphazard, particularly for more junior researchers. In addition, there is no coordinated system that provides such support to investigators. Also, the fractured nature and geographical barriers of the Mountain West have impaired the effective integration and dissemination of clinical research design, epidemiology, and biostatistics support, collaboration, and training. In order to overcome these barriers, the CTR-IN will provide local and central contact points for clinical and translational researchers who need assistance in developing study design, biostatistical methods, and epidemiological design. This will foster an energetic and productive climate for clinical and translational research and facilitate research for all investigators, including new and junior investigators.