7th Ataxia Investigators Meeting, From Bench to Bedside: Entering a New Era of Ataxia Therapies

项目总结/摘要 共济失调是一种致残和经常致命的神经系统疾病，由多种遗传和 获得性病因第七届共济失调研究者会议，“AIM 2018：从实验室到床边：进入一个 共济失调治疗的新时代”将汇集一个国际研究人员名册，以解决各种各样的问题。 共济失调的病因，更好地定义共济失调的致病基础，探索治疗途径，促进可靠的试验 在共济失调，并帮助建立未来的领导者在共济失调研究领域。会议将重点讨论 最新的科学进展和新兴的综合治疗方法， 目的：1）完善我们对小脑功能和功能障碍的理解; 2）开发和评估 治疗策略; 3）促进共济失调的稳健临床试验的发展; 4）帮助建立未来 通过促进年轻研究人员的参与，培养共济失调研究的领导者; 5）将受训人员纳入 与共济失调患者及其家属接触。AIM 2018将是一个关键机制， 在共济失调研究和治疗方法方面的合作和讨论，这一点现在尤其重要 该领域正在进入有意义的多中心临床试验阶段， 欧洲AIM 2018会议，附属于最大的共济失调年会并与之重叠 基金会在该国发生在同一家酒店，将最大限度地发挥这次会议的影响，科学家 病人也一样。

PROJECT SUMMARY/ABSTRACT Ataxia, a disabling and frequently fatal neurological disorder, results from a wide variety of genetic and acquired etiologies. The 7th Ataxia Investigators' Meeting, “AIM 2018: From Bench to Bedside: Entering a New Era of Ataxia Therapies” will assemble an international roster of investigators to address the diverse causes of ataxia, better define the pathogenic basis of ataxia, explore routes to therapy, facilitate robust trials in ataxias, and help to establish future leaders in the ataxia research field. The conference will focus on the most recent scientific advances and emerging integrative approaches toward therapy, with the following objectives: 1) refine our understanding of cerebellar function and dysfunction; 2) develop and evaluate therapeutic strategies; 3) facilitate development of robust clinical trials in ataxias; 4) help to establish future leaders of ataxia research by facilitating the involvement of young investigators; and 5) bring trainees into contact with ataxia patients and their families. AIM 2018 will represent a critical mechanism to facilitate collaboration and discussion on ataxia research and therapeutic approaches, which is especially important now that the field is entering the phase of meaningful, multi-center clinical trials both in the United States and Europe. The AIM 2018 meeting, affiliated and overlapping with the annual meeting of the largest ataxia foundation in the country occurring at the same hotel, will maximize the impact of this meeting for scientists and patients alike.