Advancing Competitive Biomedical Research in Puerto Rico

 描述(由申请人提供)：波多黎各IDEA卓越生物医学研究网络(PR-INBRE)的这一续期申请将加强波多黎各作为进行多学科研究的平台来加强波多黎各生物医学研究能力的最初目标。这一目标将得到四个专题重点领域的支持：神经科学、分子医学、药物开发、环境和行为研究；并得到前一个供资期间建立的生物信息学基础设施的支持。新的牵头机构--波多黎各大学医学校园(UPR-MSC)是一个完整的学术卫生中心，也是一个主要为拉美裔服务的机构。UPR-MSC将加强牵头机构和伙伴机构之间的合作，提高其生物医学相关研究的能力，并为由11个主要本科机构(PUI)、3个医学院、1个专业学校和2个研究密集型机构组成的17个成员的PR-INBRE网络提供科学领导和后勤支持。PR-INBRE预计将惠及约89,712名攻读STEM、医学和生物医学学科博士、医学、硕士和理科学士学位的全日制学生。PR-INBRE的行政、生物信息学、仪器和教育核心将为教师、博士后研究员、本科生、医学和研究生实施创新的研究培训和职业发展活动。这些活动将由一个发展研究项目方案赞助，该方案支持为年轻研究人员提供各种资金和指导倡议。还将支持学生的研究指导和工资支持，INBRE机构的客座演讲者计划，技术培训研讨会，专业课程和旅行奖。PR-INBRE的具体目标是：1-加强PR-INBRE网络，领导和伙伴机构的生物医学专业知识和研究基础设施。2-促进研究人员、博士后研究员、研究中代表性不足群体的研究生和本科生的发展。3--提高生物医药从业人员的科技能力。改善对研究项目调查人员的监督，更加强调研究导师的有效性，以及加强对每项计划活动的外部和内部评估和结果跟踪，将是该计划的一个特点。通过与地区INBRE和COBRE项目的合作，我们将利用我们的研究资源和科学专长，丰富研究和培训机会的数量和质量。统一的管理结构加上对INBRE目标的坚定机构承诺，将创造一种培养环境，提高网络中的研究生产率和质量，并导致招聘和留住有才华的研究人员。我们希望维持一个强有力的生物医学培训渠道，促进生物医学劳动力的多样性，并最终通过研究影响人类健康。

 DESCRIPTION (provided by applicant): This renewal application of the Puerto Rico IDeA Networks of Biomedical Research Excellence (PR-INBRE) will reinforce the original goal to strengthen the biomedical research capacity in Puerto Rico by serving as a platform for conducting multidisciplinary research. This objective will be augmented by the support of four thematic focus areas: Neuroscience, Molecular Medicine, Drug Development, Environmental and Behavioral Research; buttressed by the Bioinformatics infrastructure developed during the previous funding period. The new lead institution, the University of Puerto Rico Medical Sciences Campus (UPR-MSC) is a complete academic health center and a predominantly Hispanic-serving institution. The UPR-MSC will strengthen collaborations between lead and partner institutions, enhance their capacity for biomedically relevant research, and provide scientific leadership and logistical support for a 17-member PR-INBRE network of 11 Primarily Undergraduate Institutions (PUIs), 3 Medical Schools, 1 Professional School, and 2 Research-intensive institutions. The PR-INBRE is expected to benefit the ~89,712 full time students pursuing Ph.D., M.D., M.S., and B.S. degrees in STEM, Medicine, and Biomedical disciplines. Administrative, Bioinformatics, Instrumentation, and Education Cores of the PR-INBRE will implement innovative research training and career development activities for faculty, postdoctoral Fellows, undergraduate, medical, and graduate students. These activities will be sponsored by a Developmental Research Project Program supporting a variety of funding and mentoring initiatives for young investigators. Also supported will be research mentoring and salary support for students, a Visiting Speaker Program for INBRE institutions, Technical Training Workshops, Specialized Courses, and Travel Awards. The Specific aims of PR-INBRE are: 1-Strengthen the PR-INBRE network lead and partner institutions' biomedical expertise and research infrastructure. 2- Contribute to the development of research faculty, postdoctoral Fellows, graduate and undergraduate students of underrepresented groups in research. 3- Enhance the science and technology competency of the biomedical workforce. Improved oversight of research project investigators and greater emphasis on effectiveness of Research Mentors coupled with intensification of external and internal evaluation and tracking of outcomes for every program activity will be a hallmark of this program. Through collaborations with regional INBRE and COBRE programs, we will leverage our research resources and scientific expertise, and enrich the number and quality of research and training opportunities. A unified administrative structure coupled with a strong institutional commitment to the INBRE goals will create a nurturing environment that will raise the productivity and quality of research in the network, and result in the recruitment and retention of talented researchers. We expect to sustain a vigorous biomedical training pipeline that contributes to diversity in the biomedical workforce, and ultimately impact human health through research.