Buffalo Clinical and Translational Research Center

联系PD/PI：墨菲，蒂莫西·F 布法罗临床和翻译研究中心 布法罗翻译联盟(BTC)，包括12个主要的学术、研究和医疗保健 机构和5个有影响力的社区合作伙伴，已经开始了全面的战略 计划为临床和转化性研究奠定坚实的基础，以响应我们的社区需求。 布法罗是纽约州人口第二多的城市，有着丰富的文化历史。分布情况： 2015年在布法罗经历健康差距的代表不足的少数族裔(50%)与预测的相似 对于2050年的美国来说，布法罗成为35年后美国面貌的一个缩影。我们的愿景是 CTSA中心将开发、测试和分享改善健康和减少健康差距的新方法 我们的社区，代表着“未来的人口”。改善我们社区和社区的健康 国家将需要在整个T1到T4翻译范围内进行创新研究。2012年， 布法罗大学开设了新的170,000平方英尺的最先进的临床和翻译研究中心 (CTRC)完全致力于临床和翻译研究。CTRC提供了一个集中的设施， 包括翻译研究实验室、临床研究中心、成像中心、实验动物设施 和一个生物仓库。CTRC和其他巨大的BTC投资建设21世纪的学术卫生 中心为CTSA创建了一个设置，以提供关键部分来转变我们带来发现的能力 实验室、诊所和社区通过分享专业知识和 作为国家联合体的一部分，对翻译科学采取创新方法。我们将把力量带到 CTSA财团，包括开发新的健康信息学工具，利用我们作为领先的 标准和本体论研究中心；开发基于社区的研究的新方法 与我们的社区合作；测试和传播基于本体的方法以共享翻译图像数据；以及 联盟中为数不多的提供全方位服务的药物开发服务公司之一。 通过CTSA，我们将1)加快开发、实施和传播新的 医疗保健干预措施及其通过跨T1的创新研究转化为社区 通过T4 SPECTRUM，2)培训和发展一支优秀和多样化的员工队伍，以确保翻译 研究人员和他们的团队拥有推进发现转化的技能和知识，3)建立 整合来自多个来源的数据并结合数据分析方法的翻译科学管道 发现诊断、治疗和预防干预措施，以及4)简化临床研究流程 以质量为重点，加强对特殊人群的招募，包括 健康差异，并加快多点临床试验的启动。在我们独特优势的基础上建设将增强 通过协作和共享专业知识和资源，我们的地方和国家CTSA网络能力。 项目摘要/摘要页272 联系PD/PI：墨菲，蒂莫西·F 布法罗临床和翻译研究中心

Contact PD/PI: Murphy, Timothy F Buffalo Clinical and Translational Research Center The Buffalo Translational Consortium (BTC), which includes 12 major academic, research and healthcare institutions and 5 influential community partners in our region, have embarked on a comprehensive strategic plan to build a strong foundation for clinical and translational research in response to our community needs. Buffalo is the second most populous city in New York State and has a rich cultural history. The distribution of underrepresented minorities who experience health disparities in Buffalo in 2015 (50%) parallels that projected for the US in 2050, making Buffalo a microcosm of what the US will look like in 35 years. The vision for our CTSA hub is to develop, test and share novel approaches to improve health and reduce health disparities in our community, which represents a “population of the future”. Improving health in our community and the nation will require innovative research across the full T1 through T4 translational spectrum. In 2012, the University at Buffalo opened the new 170,000 ft2 state-of-the-art Clinical and Translational Research Center (CTRC) devoted entirely to clinical and translational research. The CTRC provides a centralized facility, including translational research laboratories, a clinical research center, an imaging center, a lab animal facility and a biorepository. The CTRC and other enormous BTC investments to build a 21st century Academic Health Center creates a setting for a CTSA to provide the key piece to transform our capacity to bring discoveries in the laboratory, the clinic and the community to benefit individual and public health by sharing expertise and innovative approaches to translational science as part of the national consortium. We will bring strengths to the CTSA consortium, including developing novel health informatics tools, leveraging our strength as a leading center on research in standards and ontologies; new approaches to community-based research developed with our community; testing and disseminating ontology-based methods to share translational image data; and one of the few full service Drug Development Services in the consortium. With a CTSA we will 1) accelerate the development, implementation and dissemination of new healthcare interventions and their translation into the community through innovative research across the T1 through T4 spectrum, 2) train and develop an excellent and diverse workforce to ensure that translational researchers and their teams have the skills and knowledge to advance translation of discoveries, 3) build a translational science pipeline that integrates data from multiple sources and combines data analysis methods to discover diagnostic, therapeutic and preventive interventions, and 4) streamline clinical research processes with a focus on quality to enhance recruitment of special populations across the lifespan and groups with health disparities, and accelerate multi-site clinical trial initiation. Building on our unique strengths will enhance both our local and national CTSA network capacity through collaboration and sharing expertise and resources. Project Summary/Abstract Page 272 Contact PD/PI: Murphy, Timothy F Buffalo Clinical and Translational Research Center