Administrative Core

项目总结/摘要 克莱姆森大学在真核病原体研究方面的基础导致了真核生物的形成。 病原体创新中心（EPIC），由受托人的大学董事会于2013年1月正式批准， 以加强这一重要的生物医学研究领域。成立该中心的理由是， 提供认可，并通过促进提高真核病原体研究在克莱姆森的实力 教师之间的互动。本建议的行政核心的具体目标是：（1）加强 CU真核病原体创新中心（EPIC），（2）培训目标研究人员， 竞争R01资金，（3）评估EPIC组织和目标培训的有效性 investigators.行政核心为真核病原体研究的两个试点项目提供资金， 招募新成员加入EPIC。还为两个核心设施的升级和改进提供了资金， 克莱姆森光成像设施和克莱姆森大学基因组学研究所为EPIC提供服务 和大学研究界。具有相关研究兴趣的杰出科学家， NIH资助的历史将作为目标研究者的导师。这些导师， 由每名目标研究者与PI和Co-PI协商后精心挑选，将提供科学专业知识 并促进目标调查人员建立合作关系。他们也将提供指导， 实验室管理、论文发表和基金撰写方面的反馈。最后，外部咨询 委员会将评估该计划，并在该COBRE的各个方面提供指导。克莱姆森大学 农业、林业和生命科学学院以及公共服务活动管理局 承诺在教师招聘方面为EPIC和COBRE提供实质性支持（具有竞争力的工资和 启动），研究生助学金，和基础设施改造。COBRE的资金和支持 将支持和加强EPIC成为一个全国知名的中心，致力于研究 真核生物病原体。

PROJECT SUMMARY/ABSTRACT Clemson University's foundation in eukaryotic pathogens research has led to the formation of the Eukaryotic Pathogens Innovation Center (EPIC), formally approved by the University Board of Trustees in January 2013, in order to strengthen this important area of biomedical research. The rationale for forming this Center was to provide recognition and enhance the strength of eukaryotic pathogen research at Clemson by promoting interactions among faculty. The Specific Aims of the Administrative Core of this proposal are: (1) to strengthen the CU Eukaryotic Pathogens Innovation Center (EPIC), (2) to train target investigators to successfully compete for R01 funding, and (3) to assess the effectiveness of the organization of EPIC and training of target investigators. The Administrative Core provides funds for two pilot projects in eukaryotic pathogen research to recruit new members to EPIC. Funds are also provided for upgrades and enhancements to two core facilities, the Clemson Light Imaging Facility and the Clemson University Genomics Institute to provide services for EPIC and the university research community. Prominent scientists with related research interests and an extensive history of NIH funding will serve as mentor for the target investigators. These mentors, who have been handpicked by each target investigator in consultation with the PI and Co-PI, will provide scientific expertise and facilitate establishment of collaborations by the target investigators. They will also provide guidance and feedback in lab management, manuscript publication, and grant writing. Finally, an External Advisory Committee will assess the program and provide guidance in all aspects of this COBRE. Clemson University, the College of Agriculture, Forestry, and Life Sciences, and the Public Services Activities Administration have pledged substantial support for EPIC and this COBRE in terms of faculty hires (with competitive salary and start-up), graduate assistantships, and infrastructural renovations. The funds from this COBRE and the support from the University will bolster and strengthen EPIC into a nationally renowned center devoted to the research of eukaryotic pathogens.