Training of the Pediatric Physician-Scientist

描述（由申请人提供）：这是华盛顿大学医学院儿科医生NICHD机构培训补助金（T32 HD 043010，儿科医生-科学家培训）的竞争性更新。我们的长期目标是利用这笔资金促进年轻儿科医生科学家的职业发展，他们将成为致力于儿童健康的生物医学研究工作的未来领导者。这项建议的目的是在完成住院医师培训或正在接受研究金培训时确定潜在的受训人员，并为他们提供为期两三年的研究 在实验室的经验，合格的导师，从临床和教学责任的保护，并与儿科相关的具体研究重点。在最近完成的资助期间，有9名优秀候选人获得了支持（包括6名妇女和1名代表不足的少数民族）。其中5人完成了培训，3人获得了K奖。我们的长期目标和目的在这次更新申请中保持不变;然而，我们通过两条途径（基础科学和转化医学）的发展显着扩大了我们计划的范围。我们将通过应用科学的最新进展来理解儿科竞技场内广泛疾病的发病机制和治疗来实现我们的长期目标。为了实现这一目标，我们将联合收割机结合华盛顿大学医学院和儿科的研究优势。我们现在已经纳入了一个新的重点领域（轨道二），即转化医学，其中包括流行病学，生物统计学，以病人为导向的研究。我们的计划将最终缩小基础生物学家和儿科临床医生之间的差距。我们有一个结构，在这个结构中， 年轻的医生将在一个受保护的环境中蓬勃发展，并将成为儿科领域不断发展的领导者。Alan L.施瓦茨博士，M.D.将继续担任私家侦探和医学博士玛丽·迪诺尔博士将担任培训主任。该计划利用了华盛顿大学医学院的34名既定调查人员，他们将担任我们学员的导师。该计划的长期目标将实现，因为它的学员有助于在未来二十年或更长时间内发展和领导儿科医生科学家。

DESCRIPTION (provided by applicant): This is a competing renewal for the NICHD Institutional Training Grant for Pediatricians (T32 HD043010, Training of the Pediatric Physician-Scientist) at Washington University School of Medicine. Our long-term objective is to utilize this funding to promote the career development of young pediatric physician scientists who will become the future leaders in the biomedical research efforts dedicated to child health. The aims of this proposal are to identify potential trainees at the completion of their residency training or in the midst of fellowship training, and to provide them with a two-three year research experience in the laboratory of a qualified mentor, protected from clinical and teaching responsibilities and with a specific research focus relevant to pediatrics. During the recently completed funding period, nine excellent candidates were supported (including six women and one under-represented minority). Five have completed training and three of these have received K awards. Our long-term objective and aims remain unchanged in this renewal application; however, we have significantly expanded the scope of our program with the development of two pathways (basic science and translational medicine). We shall achieve our long-term objective by applying the recent advances in the sciences to an understanding of the pathogenesis and treatment of a broad spectrum of diseases within the Pediatric arena. In order to accomplish this, we shall combine the established areas of investigative strengths of the Washington University School of Medicine and the Department of Pediatrics. We have now incorporated a new area of emphasis (Track II); namely, translational medicine which includes epidemiology, biostatistics, and patient- oriented research. Our program will ultimately close the gap between basic biologists and pediatric clinicians. We have in place a structure in which bright, motivated, young physicians shall flourish in a protected environment and will emerge as leaders in an evolving area of Pediatrics. Alan L. Schwartz, Ph.D., M.D. will continue to serve as P.I. and Mary Dinauer, M.D., Ph.D. will serve as Training Director. The program takes advantage of 34 established investigators across Washington University School of Medicine who will serves as mentors to our trainees. The long-term goals of the program will be realized as its trainees contribute to the development of and leadership as pediatric physician-scientists during the next two or more decades.