HISTOPATHOLOGY CORE

摘要 C核心是组织病理学的核心，自其成立以来，一直是私营部门小组工作的宝贵成本效益资产。 盗梦空间。它为PPG调查人员提供了广泛的组织学服务，包括改进 它保持了核心的最先进状态。核心组织提供的组织学服务包括组织 加工、石蜡包埋、切片、染色、免疫组织化学。核心人员也有 协助研究人员收集动物组织进行组织学研究。新的服务已经上线 因为它们已经商业化了。核心有一个组织的激光捕获显微镜 最近升级的显微解剖支持免疫荧光检测。这已经被用在 项目三.核心还购买了一台组织微点样器。此外，酷睿还提供数字 对选定的组织学发现进行显微摄影，以便为调查人员编制程序。在过去的几年里，核心的组织学 所有调查人员都在不同程度上使用了服务--除了非人类的旧项目I 灵长类动物只在很小的程度上利用了核心，因为灵长类中心有自己的 组织学/病理学实验室。对于即将到来的PPG，所有三个项目都将使用核心服务。托马斯博士 监督项目，并根据需要提供个人建议和帮助。Gendron女士是一位杰出的 与PPG团队成员一起进行日常工作的组织学家。她工作效率很高。她特别是 擅长运用免疫组织学技术。PPG的成员被允许将他们的组织 在他们的个人项目中不收取额外费用。这在经济上是可能的，因为我们的 与俄亥俄州立大学奈特癌症研究所合作。

Abstract Core C the histopathology core has been an invaluable cost effective asset to the work of the PPG since its inception. It has provided a wide variety of histological services to PPG investigators including improvements that maintain the state of the art status of the core. The histology services provided by the Core include tissue processing, paraffin embedding, sectioning, staining and immunohistochemistry. Core personnel have also assisted investigators in the collection of animal tissues for histologic studies. New services have come on-line as they have become commercially available. The Core has a laser capture microscope for tissue microdissection that was recently upgraded to support immunofluorescence detection. This has been used on Project III. The Core has also purchased a tissue microarrayer. In addition, the Core provides digital photomicrographs of selected histologic findings to program investigators. In past years, the Core's histology services have been used to a varying extent by all of the investigators - except for the old Project I in nonhuman primates which took advantage of the core in only a minor way because primate center has its own histology/pathology lab. For the upcoming PPG all three of the projects will use the core services. Dr. Thomas oversees the program and offers personal advice and assistance as needed. Ms. Gendron is an outstanding histologist who works day to day with members of the PPG team. She is highly effective. She is especially adept at getting immunohistology techniques to work. Members of the PPG are allowed to have their tissues processed at no additional charge to their individual projects. This is financially possible because of our partnership with the OHSU Knight Cancer Institute.